Results 71 to 80 of about 1,408,925 (327)

Delivery System Reform Tracking: A Framework for Understanding Change [PDF]

, 2011
Proposes a framework for tracking progress on delivery system reforms such as patient-centered medical homes and accountable care organizations by assessing structures, capabilities, incentives, and outcomes.
Alain Enthoven, Anne-Marie J. Audet, Cathy Schoen, Francis J. Crosson, Laura Tollen, Murray Ross, Nancy Taylor   +6 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Factors associated with the non-retention of health sector employees recruited in Iran: a survival analysis

BMC Health Services Research
Background Health staff are an essential component of the health system and a significant factor in improving health outcomes. As a result, without a suitable number of trained and supported workforces, health-related goals will not be achieved.
Behrooz Rahimi, Faeze Ghasemi Seproo, Roghayeh Khalilnezhad, Mahmoud Khodadost, Tahereh Kashkalani, Fatemeh Younesi, Behzad Tadayon, Mahmood Samadpour, Mahboubeh Bayat   +8 more
doaj   +1 more source

Views of policy makers and health promotion professionals on factors facilitating implementation and maintenance of interventions and policies promoting physical activity and healthy eating: results of the DEDIPAC project

BMC Public Health, 2017
Background The uptake, implementation, and maintenance of effective interventions promoting physical activity (PA) and a healthy diet and the implementation of policies targeting these behaviors are processes not well understood.
Saskia Muellmann, Berit Steenbock, Katrien De Cocker, Marieke De Craemer, Catherine Hayes, Miriam P. O’Shea, Karolina Horodyska, Justyna Bell, Aleksandra Luszczynska, Gun Roos, Lars Jørun Langøien, Gro Rugseth, Laura Terragni, Ilse De Bourdeaudhuij, Johannes Brug, Claudia R. Pischke   +15 more
doaj   +1 more source

Summary Progress Report: Active Living by Design Grant Program [PDF]

, 2009
Evaluates the outcomes of RWJF's five-year initiative designed to enhance built environments and facilitate physical activity. Examines community partnerships' impact on fundraising, media coverage, programs, policy and planning, and physical ...

core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

What is brain health?

Cerebral Circulation - Cognition and Behavior
The call to optimize brain health is now a local, regional and global priority. Organizations such as the World Health Organization, Centers for Disease Control and Prevention and Alzheimer's Association, American Academy of Neurology, World Federation ...
Philip B. Gorelick, Farzaneh A. Sorond
doaj   +1 more source

Home Depot Foundation - 2009 Annual Report [PDF]

, 2010
Contains videos of president's message, 2008 highlights, and national impact; program information; grantee profiles; grant information by state; awards; and lists of corporate donors, board members, staff, and supplier advisory committee ...

core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source