Results 121 to 130 of about 706,349 (318)

The prevalence of Type 2 diabetes and its associated health problems in a community-dwelling elderly population.

, 2009
AIMS: Prevalence estimates of Type 2 diabetes and its associated health problems in elderly populations are rare, especially in the very elderly. METHODS: A sample of 15 095 community-dwelling older people aged > or = 75 years were assessed.
Fletcher, AE, Fletcher, A. E., Hewitt, J, Smeeth, L, Smeeth, L., Hewitt, J., Bulpitt, CJ, Bulpitt, C. J.   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Elderly health, wealth and coresidence with adult children in rural India

, 2006
Little is known about the living conditions of a growing number of elderly in India who predominantly coreside with their children. Mutual sharing of responsibilities is important in coresidency arrangements involving exchange of financial and other ...
Pal, S
core  

Healthy Residential Environments for the Elderly

, 2014
This study aims to analyze the environmental elements of residential facilities for elderly people by using Antonovsky’s salutogenic concept. The relationship between the environment and health is clearly identified.
Heshmati, Almas,, Yeo, M.,
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Estudo longitudinal dos aspectos multidimensionais da saúde de idosos institucionalizados

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: Analisar a evolução de aspectos multidimensionais da saúde de idosos institucionalizados no município de Goiânia no seguimento de dois anos. MÉTODOS: Foi realizado estudo clínico observacional longitudinal prospectivo.
Ruth Losada de Menezes, Maria Márcia Bachion, Joaquim Tomé de Souza, Adélia Yaeko Kyosen Nakatani   +3 more
doaj   +1 more source

Using Statistics Canada LifePaths Microsimulation Model to Project the Health Status of Canadian Elderly [PDF]

Complex population projections usually use microsimulation models; in Canada, Statistics Canada has developed a global dynamic microsimulation model named LifePaths in the Modgen programming language to be used in policy research.
Yann Décarie, Jacques Légaré
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Development of the short form of the Korean health literacy scale for the elderly

, 2013
We developed and examined a shortened form of the Korean Health Literacy Scale (KHLS) with a sample of 543 elderly in South Korea. Rasch analysis of the KHLS was conducted to examine the unidimensionality of the scale, along with a confirmatory factor ...
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core   +1 more source