In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim+11 more
wiley +1 more source
Personalizing product sets to individual health priorities increases the healthfulness of hypothetical food choices in US adults. [PDF]
Gustafson CR+3 more
europepmc +1 more source
Social Accountability and Regional Health Priorities in Medical Education. [PDF]
Hershberger PJ+3 more
europepmc +1 more source
Research priorities in occupational health in Italy [PDF]
Sergio Iavicoli+5 more
openalex +1 more source
Health and nutrition: emerging and reemerging issues in developing countries [PDF]
CONTENTS: Brief 1. Overview / Rafael Flores Brief 2. The Global Burden of Disease / Alan D. Lopez Brief 3. HIV/AIDS / Anthony Barnett and Gabriel Rugalema Brief 4. Malaria / Andrea Egan Brief 5. Tuberculosis / Ariel Pablos-Mendez Brief 6.
Flores, Rafael, ed.+1 more
core
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
Incorporating individually defined brain health priorities in clinical trial outcomes: the electronic Person-Specific Outcome Measure approach in the United States. [PDF]
Saunders S+8 more
europepmc +1 more source
One Pandemic, Two Solutions: Comparing the U.S.-China Response and Health Priorities to COVID-19 from the Perspective of "Two Types of Control". [PDF]
Lyu S, Qian C, McIntyre A, Lee CH.
europepmc +1 more source