Results 71 to 80 of about 12,415,763 (266)

Associations between maternal race, socioeconomic status and shoulder dystocia: a population-based retrospective cohort study in Ontario Canada

open access: yesBMC Pregnancy and Childbirth
Background Shoulder dystocia is a severe and emergent adverse perinatal complication. Existing literature suggests that the risk of shoulder dystocia varies by race and socioeconomic status, but research in this area is lacking in Canada.
Qun Miao   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Data resource profile: National Cancer Registry Ireland

open access: yesESMO Real World Data and Digital Oncology
Background: National Cancer Registry Ireland (NCRI) is the state agency responsible for collecting and analysing data on all cancer patients to help improve health outcomes in Ireland.
M.T. Redaniel   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Cancer in Ireland 1994-2015 with estimates for 2015-2017: Annual Report of the National Cancer Registry

open access: yes, 2017
This is the 22nd annual statistical report of the National Cancer Registry. This report summarises cancer incidence, mortality and survival in Ireland for the period 1994-2015, and provides projected estimates for incidence for the most recent three-year
National Cancer Registry Ireland (NCRI)
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Registro Sanitario, logros, debilidades y proyecciones al cierre del 2013

open access: yesRevista Cubana de Higiene y Epidemiología
Se presenta un breve comentario acerca del trabajo desarrollado por el Registro Sanitario en el año 2013, con la finalidad de informar a los interesados en este tema sobre los logros, debilidades y proyecciones de trabajo que se ha trazado este colectivo
Maritza T Suárez Pita   +1 more
doaj  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

The burden of cancers associated with HIV in the South African public health sector, 2004–2014: a record linkage study

open access: yesInfectious Agents and Cancer, 2019
Introduction The impact of South Africa’s high human immunodeficiency virus (HIV) burden on cancer risk is not fully understood, particularly in the context of antiretroviral treatment (ART) availability.
Tafadzwa Dhokotera   +7 more
doaj   +1 more source

Data quality and completeness at the Irish National Cancer Registry

open access: yes, 2012
The Irish National Cancer Registry (NCR) is a statutory body that began full registration of all cancers in the Republic of Ireland in January 1994. The reporting of cancer is not mandatory in Ireland. However the NCR makes considerable effort to ensure
National Cancer Registry Ireland (NCRI)
core  

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