Results 81 to 90 of about 65,601,074 (263)

National Mental Health Research Strategy [PDF]

This first national mental health research strategy for Ireland presents a unique opportunity to create a thriving mental health research system that can support mental health and wellbeing for all.
Health Research Board
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Health research in action 2021

, 2021
Annual report for the HRB, which funds and performs research in ...
Health Research Board
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Artificial Intelligence and Data Mining in Health Research (AI/MDRS)

McGill Journal of Medicine, 2022
The Cardiometabolic Health and Obesity Research Network (rrCMDO)
doaj   +1 more source

From inclusion to empowerment: advancing equity through co-research with people living with dementia

Frontiers in Dementia
Too often, people living with dementia are spoken for rather than spoken with. This reflects deeply embedded assumptions/biases about people living with dementia in our society.
Lillian Hung, Joey Wong, Karen Lok Yi Wong, Emily Ong, Granville Johnson, Helen Rochford-Brennan, Jim Mann, Lester Gierach, Lynn Jackson, Mario Gregorio, Mary Beth Wighton, Mary Beth Wighton, Phyllis Fehr   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Public trust in health research: are we doing enough? Irish Health Research Forum recommendations and event report [PDF]

Public trust is essential for the health of the nation. Without it, people will reject, misunderstand or under-use the health research which can save and enhance their lives.
Health Research Charities Ireland
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Health Research Board annual report 2020 part 2

, 2022
The Board is responsible for keeping adequate accounting records which disclose, with reasonable accuracy at any time, its financial position and enables it to ensure that the financial statements comply with Article 27 of the Health Research Board
Health Research Board
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Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source