Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
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Retraction: Health risk assessment of exposure to chlorpyrifos in pregnant women using deterministic and probabilistic approaches. [PDF]
PLOS One Editors.
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In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
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Toxic Metal Content in Mexican Propolis: A Human Health Risk Assessment. [PDF]
Balderrama-Carmona AP +9 more
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Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
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Health Risk Assessment of Dietary Arsenic Exposure and Selenium Deficiency in Tibet Based on In Vitro Gastrointestinal Simulation. [PDF]
Sun J +7 more
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Ethical Foreground and Background in Adult Educator Work
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
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From environmental occurrence to human exposure: multisystem toxicity, immune-relevant mechanisms, and gaps in health-risk assessment of liquid crystal monomers. [PDF]
Zhang H +5 more
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ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
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Development of a soil cadmium bioaccessibility prediction model for human health risk assessment. [PDF]
Cao J +7 more
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