Results 161 to 170 of about 13,219,553 (356)

Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device

iScience
Summary: The CH-VAD is a fully magnetically levitated left ventricular assist device (LVAD) designed for optimized hemocompatibility. This study evaluates the clinical outcomes of 77 patients implanted with the CH-VAD across seven centers in China from ...
Yifan Lu, Shuanglei Zhao, Jie Han, Qiang Lv, Xin Du, Zhengdong Hua, Keli Huang, Zhenwei Ge, Xiaoning Sun, Dan Zhu, Yongfeng Shao, Hongjia Zhang, Ming Gong   +12 more
doaj  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Consultation Aid from the Standpoint of Health Science

, 1967
Kunizo Fukuta
openalex   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Protocol for implementing the nested model for AI design and validation in compliance with AI regulations

STAR Protocols
Summary: Here, we present a protocol for implementing the nested model for developing and validating artificial intelligence (AI) systems in compliance with AI regulations.
Akshat Dubey, Zewen Yang, Aleksandar Anžel, Georges Hattab   +3 more
doaj  

Students’ Ideas Regarding Science and Pseudo-science in Relation to the Human Body and Health

, 1970
Mats Lundström, Anders Jakobsson
openalex   +2 more sources

Emerging disciplines in the health sciences and their impact on health sciences libraries: the behavioral sciences.

Bulletin of the Medical Library Association, 1996
Interest in human behavior has always been present in schools of medicine. Particularly since World War II, this interest has been amplified, as shown by a number of trends. These include increasing time in the medical school curriculum for the teaching of the behavioral sciences, increasing numbers of people on medical school faculties who are ...
openaire   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Compartment-specific antibody correlates of protection to SARS-CoV-2 Omicron in macaques

iScience
Summary: Antibodies represent a primary mediator of protection against respiratory viruses. Serum neutralizing antibodies (NAbs) are often considered a primary correlate of protection.
Xin Tong, Qixin Wang, Wonyeong Jung, Taras M. Chicz, Ross Blanc, Lily J. Parker, Dan H. Barouch, Ryan P. McNamara   +7 more
doaj