Results 91 to 100 of about 225,238 (310)

British Asian families and the use of child and adolescent mental health services: a qualitative study of a hard to reach group [PDF]

open access: yes, 2007
We explored attitudes to and experiences of Child and Adolescent Mental Health Services (CAMHS) among families of South Asian origin who are underrepresented as service-users in an area of a Scottish city with a high concentration of people of South ...
White, Ishbel   +5 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Hospital services: empowerment of physical disabled people in the construction of spaces available

open access: yesOnline Brazilian Journal of Nursing, 2009
In Brazil, with regard to public policies for disable persons with barriers in access to health services1, there are challenges for implementation.
Antônia Eliana de Araújo Aragão   +1 more
doaj  

Effect of primary health care on the association between multimorbidity and emergency service utilization: National Health Survey, 2019 [PDF]

open access: yesRevista Brasileira de Epidemiologia
Objective: To examine the effect of Primary Health Care (PHC) on the association between multimorbidity and emergency service utilization among adults in Brazil.
Larissa Carolina Xavier Lacerda Lamonato   +2 more
doaj   +1 more source

Challenges for ensuring availability and accessibility toin health care services under Brazil’s unified health system (SUS)

open access: yes, 2017
Shortages and imbalances in the distribution of the health workforce, are social and political problems that, along with the socio-economic inequality, reduce the access of the population to the health services.
Dal Poz, Mario Roberto   +7 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

How to make an eye clinic more accessible for people with low vision

open access: yesCommunity Eye Health Journal, 2012
How to make an eye clinic more accessible for people with low vision through good patient flow, use of colour, contrast and lighting and by assisting patients.
Jaya Srivastava
doaj  

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