Results 71 to 80 of about 746,126 (311)

Enhancing Health Care Accessibility and Equity Through a Geoprocessing Toolbox for Spatial Accessibility Analysis: Development and Case Study

open access: yesJMIR Formative Research
BackgroundAccess to health care services is a critical determinant of population health and well-being. Measuring spatial accessibility to health services is essential for understanding health care distribution and addressing ...
Soheil Hashtarkhani   +2 more
doaj   +1 more source

Dialectical hermeneutics: an experience as a method of analysis in research on the user access to pharmaceutical services [PDF]

open access: yesRevista Brasileira em Promoção da Saúde, 2012
Objective: To describe the application of dialectical hermeneutics as a method of analysis in research on pharmaceutical services. Data Synthesis: This is the description of a qualitative approach method of analysis, used in a research having as its ...
Tatiane de Oliveira Silva Alencar   +2 more
doaj  

Attitudes, Knowledge, and Beliefs on Cancer and its Prevention in Northwestern Rural Alaska [PDF]

open access: yes, 2012
Rural Alaskans face unique challenges in accessibility. Most villages and cities are not connected to road systems, limiting travel between rural and urban areas. This also limits connectivity between small communities.
Schmidt, Jenna
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Use of Health Care Services and Associated Factors among Women.

open access: yesIranian Journal of Public Health, 2014
To estimate the prevalence and analyze factors associated with both public and private health services utilization in women population in a western district of Iran.A cross-sectional study with 1200 individuals aged 18-49 years carried out in different ...
Nader Esmailnasab   +3 more
doaj  

Switching on the remote: a new perspective on accessibility in remote Australia [PDF]

open access: yes, 2016
Learning Communities: International Journal of Learning in Social Contexts by https://www.cdu.edu.au/northern-institute/lcj is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.In remote Australia, access to people, goods,
Kohen, A, Spanodine, Bruno
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Geographic accessibility to hospital childbirths in Brazil (2010–2011 and 2018–2019): a cross-sectional studyResearch in context

open access: yesThe Lancet Regional Health. Americas
Summary: Background: Delays in obstetric care are associated with adverse maternal outcomes, while long-distance travel for delivery is associated with high neonatal mortality and increased maternal morbidity. Distance and travel time are key components
Priscila Costa Albuquerque   +5 more
doaj   +1 more source

Evaluation of the quality of Primary Health Care services for children : reflections on the feasibility of using the Brazilian version of the Primary Care Assessment Tool as a routine assessment tool [PDF]

open access: yes, 2019
Objective To assess the quality of the Primary Health Care services provided to children and the feasibility of using the Brazilian version of Primary Care Assessment Tool (PCAT-Brazil) as a routine quality assessment tool.
Demarzo, Marcelo   +6 more
core   +2 more sources

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