Results 51 to 60 of about 225,238 (310)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Accessing Health Information and Health Services

European Journal of Health Communication
European health communication is rich and diverse in terms of international perspectives, scientific approaches and topics. The ECREA Aarhus Best Papers special issue showcases this diversity. It features the best papers presented at the health communication section of the ECREA conference, which took place in Aarhus in 2022.
Rita Araújo, Julia C. M. Van Weert
openaire   +4 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Spatial variation in Aboriginal and Torres Strait Islander people's access to primary health care [PDF]

, 2015
The report shows that overall, Australian Government funded Indigenous-specific primary health-care services appear to be well positioned relative to the geographic distribution of Aboriginal and Torres Strait Islander people and to the distribution of ...
Australian Institute of Health and Welfare
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Geographic accessibility to hospital childbirths in Brazil (2010–2011 and 2018–2019): a cross-sectional studyResearch in context

The Lancet Regional Health. Americas
Summary: Background: Delays in obstetric care are associated with adverse maternal outcomes, while long-distance travel for delivery is associated with high neonatal mortality and increased maternal morbidity. Distance and travel time are key components
Priscila Costa Albuquerque, Lucas Lopes Felipe, Juliana Freitas Lopes, Wagner de Souza Tassinari, Fabio Zicker, Bruna de Paula Fonseca   +5 more
doaj   +1 more source

Accessibility and utilization of occupational health services

Scandinavian Journal of Work, Environment & Health, 1996
The purpose of this study was to evaluate employees' utilization of occupational health services in three Dutch companies in which the access to such services (open consultation hour, summoning and periodic health examination) is organized differently.
openaire   +3 more sources

Web accessibility diagnosis, improvement and maintenance [PDF]

, 2007
Context: This thesis examines how organisations create and maintain their web pages with particular focus on ensuring pages are accessible. It also investigates the potential for using a Tree-Map based tool to support such web maintenance and process ...
Bailey, John Oliver
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Desregulación y equidad: el proceso de reconversión de Obras Sociales en Argentina

Cadernos de Saúde Pública
Las Obras Sociales constituyen la base de la organización de la Seguridad Social Médica en Argentina. Lejos de tener un carácter equitativo, estas instituciones reproducen las desigualdades de ingresos vigentes en la actividad económica, provocando ...
Liliana Findling, María Arruñada, Ezequiel Klimovsky   +2 more
doaj   +2 more sources