Results 121 to 130 of about 746,126 (311)

Dynamics Governing Women's Decision on Reproductive Health Matters: Reflections from a Qualitative Study in Central India [PDF]

, 2005
One of the major challenges of Reproductive and Child Health Programme in India is addressing the barriers in communication and improve dialogue between diverse stakeholders, particularly women in the community.
Saha, Somen
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Relatively Inaccessible Abundance: Reflections on U.S. Health Care [PDF]

Outsiders' views of American health care - and Canadian views in particular - contains this paradox: ready access to excellent high tech services for those who can pay but unfortunately too expensive for many Americans; in essence, inaccessible abundance.
Ivy Lynn Bourgeault
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Determinants of maternal health care utilisation in India : Evidence from a recent household survey [PDF]

In India, utilisation of basic health services has remained poor. The reasons may be low levels of household income, high illiteracy and ignorance, and a host of traditional factors.
Shariff, Abusaleh, Singh, Geeta
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Spatial analysis of accessibility to support decision-making in urban investments : a case in Amazonia - Brazil [PDF]

, 2013
City planning processes are often supported by decision-making methods that involve selection, evaluation and combination of several factors. Also, nowadays, the accessibility is one important issue for the development of cities.
Ramos, Rui A. R., Rodrigues, Daniel Souto, Tobias, Maisa Sales Gama   +2 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Operacionalizando as categorias acesso e descentralização na análise de sistemas de saúde

Cadernos de Saúde Pública
O artigo apresenta proposta de operacionalização das categorias acesso e descentralização em modelo de análise de sistemas de saúde. Admite a hipótese de que se o sistema de saúde é descentralizado, ele vai permitir maior acesso dos usuários ao sistema ...
Virginia Alonso Hortale, Manoela Pedroza, Maria Luiza Garcia Rosa   +2 more
doaj  

How to make an eye clinic more accessible for people with low vision

Community Eye Health Journal, 2012
How to make an eye clinic more accessible for people with low vision through good patient flow, use of colour, contrast and lighting and by assisting patients.
Jaya Srivastava
doaj