Results 141 to 150 of about 688,867 (354)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Investigating The Accessibility Of Uninsured Population To Health Services In Greece [PDF]

open access: bronze, 2015
P Polyzou   +5 more
openalex   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey   +17 more
wiley   +1 more source

Acessibilidade a serviços de saúde bucal por pessoas idosas: uma revisão integrativa

open access: yesRevista Brasileira de Geriatria e Gerontologia
OBJETIVO: Analisar as evidências científicas publicadas relacionadas à acessibilidade de pessoas idosas aos serviços de saúde bucal. METODOLOGIA: Utilizaram-se as bases de dados MEDLINE, LILACS e BBO, empregando como descritores: "idoso", "saúde bucal" e
Silvia Carréra Austregésilo   +4 more
doaj   +1 more source

Politics, policies, pronatalism, and practice: availability and accessibility of abortion and reproductive health services in Turkey [PDF]

open access: bronze, 2016
Katrina MacFarlane   +5 more
openalex   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock   +8 more
wiley   +1 more source

Geographic accessibility to hospital childbirths in Brazil (2010–2011 and 2018–2019): a cross-sectional studyResearch in context

open access: yesThe Lancet Regional Health. Americas
Summary: Background: Delays in obstetric care are associated with adverse maternal outcomes, while long-distance travel for delivery is associated with high neonatal mortality and increased maternal morbidity. Distance and travel time are key components
Priscila Costa Albuquerque   +5 more
doaj   +1 more source

Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji   +9 more
wiley   +1 more source

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