Results 61 to 70 of about 2,534,664 (269)

'Working our way to health': Final Evaluation Report [PDF]

, 2009
This summary presents the findings of an independent evaluation of the ‘Working our Way to Health’ programme. This programme was delivered by Sefton PCT, funded through the Neighbourhood Renewal Fund, and was aimed at improving the health of men in three
Hacking, S, Robertson, S, Robinson, M
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Insights into the oral health crisis amongst pre-schoolers in Aotearoa/New Zealand: a discourse analysis of parent/caregiver experiences

BMC Oral Health, 2020
Background The oral health of pre-schoolers is garnering international as a crisis as good oral health is a key precursor to positive health outcomes. Internationally, and within Aotearoa/New Zealand, responses been restricted to those based in a medical
Michael Roguski, Karen McBride-Henry
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Are boys more vulnerable to stunting? Examining risk factors, differential sensitivity, and measurement issues in Zambian infants and young children

BMC Public Health
Background Stunting remains a considerable public health problem globally, and sex differences in prevalence have been documented. While many risk factors for stunting have been identified, few studies examine how these factors may contribute to sex ...
Amanda L. Thompson, Mathews Onyango, Patricia Sakala, John Manda, Edna Berhane, Mary Pat Selvaggio, Agnes Aongola, Stephanie L. Martin   +7 more
doaj   +1 more source

Change in Contraceptive Use Within South Carolina Medicaid Following the Choose Well Contraceptive Access Initiative: Did COVID-19 Alter the Trends?

Women's Health Reports
Objectives: COVID-19 hit at the midpoint of Choose Well, a statewide contraceptive access initiative commenced in South Carolina (SC) in 2017. This study assessed whether the pandemic altered the trends in contraceptive use among SC Medicaid during the ...
Wondi Samuel Manalew, Nathan Hale, Michael G. Smith, Amal J. Khoury   +3 more
doaj   +1 more source

The Role of Community Centre-based Arts, Leisure and Social Activities in Promoting Adult Well-being and Healthy Lifestyles [PDF]

, 2013
Developed countries are experiencing high levels of mental and physical illness associated with long term health conditions, unhealthy lifestyles and an ageing population.
Abdallah, Aiken, Buck, Marmot, Mat Jones, Newbigging, Rankin, Renton, Richard Kimberlee, Simon Evans, South, Toity Deave, Wareham, Wilkinson   +13 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Living with breast cancer: Patients’ journey within the Greek National Health System

Forum of Clinical Oncology, 2015
Background: Process mapping (a patient-centred method) and recording the medical, nursing and administrative staff’s views involved in the provision of care help us understand patients’ experience regarding the constraints, delays and bottlenecks of ...
Kaitelidou Daphne, Kalogeropoulou Maria, Katostaras Theofanis, Konstantakopoulou Olympia, Minogiannis Panagiotis, Skitsou Alexandra, Siskou Olga, Charalampous Georgios, Ardavanis Alexandros, Liaropoulos Lykourgos   +9 more
doaj   +1 more source

Achieving Universal Coverage Through Comprehensive Health Reform: The Vermont Experience [PDF]

, 2009
Provides an overview of Vermont's comprehensive health reform and the interim results of a two-year evaluation of its impact on the affordability of coverage and access to services, as well as its sustainability.
Brian Robertson, Kira Rodriguez, Ronald Deprez, Sherry Glied, Steven Kappel   +4 more
core