Results 71 to 80 of about 1,367,738 (299)

Employment in long-term care: Report on Poland [PDF]

, 2014
The report discusses the formal long-term care workforce in Poland. It presents past and future trends in the development of LTC employment. Authors collected scattered statistical information, estimated lacking data and projected future growth in the ...
Golinowska, Stanislawa, Kocot, Ewa, Sowa, Agnieszka   +2 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

An ecological study on the relationship between supply of beds in long-term care institutions in Italy and potential care needs for the elderly [PDF]

, 2009
Background The ageing population in Europe is putting an ever increasing demand on the long-term care (LTC) services provided by these countries. This study analyses the relationship between the LTC institutional supply of beds and potential care needs ...
Gianfranco Damiani, Simona C Colosimo, Lorella Sicuro, Alessandra Burgio, Alessandra Battisti, Alessandro Solipaca, Giordana Baldassarre, Roberta Crialesi, Giulia Milan, Tiziana Tamburrano, Walter Ricciardi, Organization for Economic Cooperation and Development, European Commission Employment, Social Affairs and Equal Opportunities DG, K Bolin, RB Saltman, K Leichsenring, M Gibson, S Hussein, MW Ribbe, N Huynh, BO Eriksen, JR Mc Whinnie, World Health Organization, GW Bohrnstedt, Istituto Nazionale di Statistica, Istituto Nazionale di Statistica, A Caiazzo, JL L Gutierrez-Fisac, AE Kunst, P Howden-Chapman, B Federico, World Health Organization, M Marmot, F Sassi, Istituto Nazionale di Statistica, R Bernabei, G Burke, Istituto Nazionale di Statistica, BJ Coleman, European Commission, EY Kim, EY Kim, YI Shyu, M Johri, Agenzia Nazionale per i Servizi Sanitari Regionali (AGE.NA.S), E Witmer   +45 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Estimates of population-level palliative care need in the UK: a descriptive analysis of mortality data before and during the COVID-19 pandemic

BMC Palliative Care
Background Existing estimates of palliative care need in the UK were produced before the COVID-19 pandemic. We sought to produce updated, population-level estimates of palliative care need for each of the four UK nations and explore how these changed ...
Erin Raquel Fantoni, Natasha Wynne, Anne M. Finucane   +2 more
doaj   +1 more source

From "best practice" to "best fit": a framework for designing and analyzing pluralistic agricultural advisory services [PDF]

"Agricultural advisory services play an important role in supporting the use of the agricultural sector as an engine of pro-poor growth and enabling small farmers to meet new challenges, such as accessing export markets, adopting environmentally ...
Anandajayasekeram, Pooniah, Benin, Samuel, Birner, Regina, Davis, Kristin, Ekboir, Javier M., Horna, Daniela, Kisamba-Mugerwa, Wilberforce, Mbabu, Adiel N., Nkonya, Ephraim, Pender, John, Spielman, David J.   +10 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Educational demands of family members of children with special health care needs in the transition from hospital to home [PDF]

Revista Brasileira de Enfermagem
Objectives: to analyze the educational demands of family members of children with special health care needs in the transition from hospital to home Methods: qualitative research conducted between February and June 2018, using the handbook on creativity ...
Meirilane Lima Precce, Juliana Rezende Montenegro Medeiros de Moraes, Sandra Teixeira de Araújo Pacheco, Liliane Faria da Silva, Daniele Santos da Conceição, Elisa da Conceição Rodrigues   +5 more
doaj   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Health needs and production of care in a health unit in a city of the northeast part of Brazil

O Mundo da Saúde, 2014
The production processes of health services should aim to meet the health needs of social groups that constitute a particular territory. Some time ago a reorganization of health services were proposed, with the assumption the production of care as a user-
Márcio Costa de Souza, Thamyres Menezes de Araújo, Flávia Alves de Andrade, Adriana de Jesus França, Jairrose Nascimento Souza   +4 more
doaj