Results 71 to 80 of about 174,424 (254)

Frequent Users of a Provincial 112 Emergency Medical Service in Türkiye: A Retrospective Cross-sectional Study

open access: yesEurasian Journal of Emergency Medicine
Aim: A small minority disproportionately burdens emergency medical services (EMS), yet frequent users of Türkiye’s 112 system remain uncharacterised. We determined the proportion, predictors, and subgroups associated with frequent EMS use. Materials and
Sefer Özkaya, Mehmet Serkan Yurdakul
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Assessing morbidity in the paediatric community

open access: yesRevista de Saúde Pública, 1999
INTRODUCTION: Morbidity information is easily available from medical records but its scope is limited to the population attended by the health services.
Escuder Maria Mercedes L   +4 more
doaj  

How many people will need palliative care in 2040? Past trends, future projections and implications for services

open access: yesBMC Medicine, 2017
Background Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many countries mean that more people ...
S. N. Etkind   +6 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Enhanced school-based vision screening in Kumasi, Ghana: a pilot study to assess feasibility

open access: yesFrontiers in Medicine
IntroductionChildhood vision loss is a public health concern in Ghana, where access to eye care is limited. This prospective cohort pilot study was conducted to examine the feasibility of an enhanced, school-based vision screening protocol among children
Afua O. Asare   +19 more
doaj   +1 more source

Necessidades de saúde das mulheres feirantes: acesso, vínculo e acolhimento como práticas de integralidade

open access: yesRevista Gaúcha de Enfermagem, 2017
RESUMO Objetivo Analisar as necessidades de saúde das mulheres feirantes do Mercado Público de um município do Nordeste do Brasil. Método Estudo qualitativo, exploratório-descritivo, com quinze mulheres feirantes de um mercado público.
Ana Hirley Rodrigues Magalhães   +5 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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