Maternal health in Jamaica : health needs, services, and utilization [PDF]
The main health issues for Jamaican women are nutrition, fertility, infection, chronic diseases, and stress and social problems. The two leading causes of adult health for women are cerebro-vascular accidents and coronary heart disease - of which high ...
Feifer, Chris Naschak
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Reducing need and demand for medical services in high-risk persons. A health education approach.
We undertook this study to identify persons with high medical use to target them for health promotion and self-management interventions specific to their problems. We compared the reductions in cost and health risk of a health education program aimed at high-risk persons with a similar program addressed to all risk levels.
J F, Fries, D, McShane
openaire +1 more source
Revisiting the Most Informed Consumer of Surgical Services: The Physician-Patient [PDF]
Little is known about the consumption of medical and surgical services by the most informed consumer in the health care market: the physician-patient.
Casabianca, Antoine +3 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Gênero e saúde no Brasil: considerações a partir da Pesquisa Nacional por Amostra de Domicílios
A mulher brasileira tem vivido mais que o homem, como ocorre em países industrializados centrais. Nesses países, paradoxalmente, as mulheres apresentam indicadores de morbidade mais altos que os homens.
Estela M.L. Aquino +2 more
doaj
Quality pathology and laboratory diagnostic services are key to improving global health outcomes: improving global health outcomes is not possible without accurate disease diagnosis [PDF]
As the health care needs of populations change in low- and middle-income countries, the demand for affordable, accurate, and timely diagnostic testing will increase substantially. The need for such testing is threefold: (1) to guide treatment of patients,
Sayed, Shahin
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Priority setting for health in the context of devolution in Kenya: implications for health equity and community-based primary care [PDF]
Devolution changes the locus of power within a country from central to sub-national levels. In 2013, Kenya devolved health and other services from central government to 47 new sub-national governments (known as counties).
Rosalind McCollum +69 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

