Results 151 to 160 of about 2,765,279 (315)

Health Status and Driving Among Community-Dwelling Older Adults. [PDF]

Healthcare (Basel)
Park S, Kang SW.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The determinants of health and health status of individuals in police custody in Australia: A scoping review. [PDF]

PLoS One
Ginnane JF, Martin C, Winter RJ, Stoové M, Walker SJ.   +4 more
europepmc   +1 more source

Understanding the Health Status of Chinese Migrant Elderly: The Interactive Effects of Social Support and Social Integration [PDF]

Zhaoyang Wang, Bo Lv, Xingmiao Feng, Kai Meng   +3 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

An Innovative Population Health Tool for Overall Health Status Assessment: Prospective Observational Study. [PDF]

JMIR Form Res
Hamid BTUHA, Oei RW, Kassim N, Oikawa R, Ishak N, Chan SY, Tey J, Watcharapichat P, Lam J, Mohammad PDNA.   +9 more
europepmc   +1 more source

Time and Health Status in Health Economics [PDF]

Health Economics, 2016
openaire   +2 more sources

Analysis of the National Institutes of Health COVID-19 Neuro Databank by geographic region and income status [PDF]

Jacqueline C. Dominguez, Krizelle Cleo Fowler, Igor J. Koralnik, Kore Liow, Encarnita Ampil, Zhi Qi, Lina Laxamana, Remy Berroya, Cecile J. Noris, Sharon B. Meropol, Andrea B. Troxel   +10 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The effect of antenatal psychological well-being on maternal health status. [PDF]

PLoS One
Shudayfat M, Taybeh EO, Alsous M.
europepmc   +1 more source