Results 51 to 60 of about 821,961 (316)

First experiences in the implementation of biometric technology to link data from Health and Demographic Surveillance Systems with health facility data. [PDF]

, 2010
BACKGROUND: In developing countries, Health and Demographic Surveillance Systems (HDSSs) provide a framework for tracking demographic and health dynamics over time in a defined geographical area.
Adwoa Serwaa-Bonsu, Herbst, Abraham J, Benjamin Clark, Reniers, Georges, Clark, Benjamin, Ijaa, Wilfred, Wilfred Ijaa, Georges Reniers, Chodziwadziwa Kabudula, Serwaa-Bonsu, Adwoa, Kabudula, Chodziwadziwa, Abraham J. Herbst, Osman Sankoh, Sankoh, Osman   +13 more
core   +1 more source

COVID-19 epidemic monitoring after non-pharmaceutical interventions: The use of time-varying reproduction number in a country with a large migrant population

International Journal of Infectious Diseases, 2020
Background: COVID-19’s emergence carries with it many uncertainties and challenges, including strategies to manage the epidemic. Oman has implemented non-pharmaceutical interventions (NPIs) to mitigate the impact of COVID-19.
Adil Al Wahaibi, Abdullah Al Manji, Amal Al Maani, Bader Al Rawahi, Khalid Al Harthy, Fatma Alyaquobi, Amina Al-Jardani, Eskild Petersen, Seif Al Abri   +8 more
doaj   +1 more source

Malaria vaccine coverage estimation using age-eligible populations and service user denominators in Kenya

Malaria Journal, 2023
Background The World Health Organization approved the RTS,S/AS01 malaria vaccine for wider rollout, and Kenya participated in a phased pilot implementation from 2019 to understand its impact under routine conditions.
Angela K. Moturi, Rose Jalang’o, Anitah Cherono, Samuel K. Muchiri, Robert W. Snow, Emelda A. Okiro   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Genomic epidemiology of Mycobacterium tuberculosis in Wales

Scientific Reports
Identification of factors contributing to tuberculosis (TB) transmission can guide targeted measures to reduce morbidity. Varying findings for factors associated with TB genomic clustering exist.
Nicole Pacchiarini, Felicity Simkin, Mark Postans, George Ahern, Jiao Song, Clare Brown, Josie Smith, Catie Williams, Matthijs Backx, Daniel Thomas, Thomas R. Connor, Christopher Williams   +11 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Quality assessment of malaria microscopic diagnosis at the Aristide Le Dantec University Hospital of Dakar, Senegal, in 2020

BMC Research Notes
Background Following WHO guidelines, microscopy is the gold standard for malaria diagnosis in endemic countries. The Parasitology-Mycology laboratory (LPM) is the National Reference Laboratory and is currently undergoing ISO 15189 accreditation.
Mamane N. Garba, Awa B. Dème, Khadim Diongue, Younousse Diédhiou, Amadou M. Mbaye, NDèye M. Dia, N’Dèye A. Seck, Daba Zoumarou, Lamine Ndiaye, Mamadou S. Yade, Baba Dièye, Aita Sène, Abdoulaye Tine, Mariama Touré, Nogaye Gadiaga, Awa Fall, Bassirou Ngom, Djiby Sow, Aliou Ndiaye, Astou Keita, Mame F. Ndiaye, Jules F. Gomis, Nana F. Diop, Guète Diallo, Ibrahima M. Ndiaye, Elhadj M. Ba, Omar Bitèye, Cheikh Ndiaye, Fama S. D. Mbodji, Pape O. Ndiaye, Tolla Ndiaye, Amy Gaye, Mouhamad Sy, Yaye D. Ndiaye, Mame C. Seck, Mouhamadou Ndiaye, Aida S. Badiane, Mamadou A. Diallo, Daouda Ndiaye   +38 more
doaj   +1 more source

An Outbreak of Aeromonas salmonicida in Juvenile Siberian Sturgeons (Acipenser baerii)

Animals, 2023
Aeromonas salmonicida is one of the major threats to world aquaculture, causing fish furunculosis and high mortality rates in cultured fish, particularly salmonids. Although Aeromonas spp.
Esther Vázquez-Fernández, Blanca Chinchilla, Agustín Rebollada-Merino, Lucas Domínguez, Antonio Rodríguez-Bertos   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source