Results 71 to 80 of about 821,961 (316)

Sedentary behaviour surveillance in Canada: trends, challenges and lessons learned

International Journal of Behavioral Nutrition and Physical Activity, 2020
Background Historical changes in the nature of sedentary activities have been observed in other countries, but it is not clear if similar trends exist in Canada.
Stephanie A. Prince, Alexandria Melvin, Karen C. Roberts, Gregory P. Butler, Wendy Thompson   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Public health surveillance applied to reproductive health [PDF]

"Public Health Surveillance Applied to Reproductive Health includes an introduction to public health surveillance and how it can be applied to reproductive health, uses of surveillance data, sources of surveillance data, types of surveillance systems ...

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Factors associated with COVID-19 deaths in Sierra Leone, March 2020 - March 2022

Journal of Interventional Epidemiology and Public Health
Introduction: Coronavirus Disease 2019 (COVID-19) is a global public health emergency that has claimed millions of lives. In Sierra Leone, limited information exists on the factors associated with COVID-19 deaths.
Stephen Lawrence Musa Kamara, Adel Hussein Elduma, Umaru Sesay, Binta Bah, Joel Francis Mansaray, Magoba Bridget, James Sylvester Squire, Amara Alhaji Sheriff, Solomon Aiah Sogbeh, Gebrekrstos Negash Gebru   +9 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Distinct African Swine Fever Virus Shedding in Wild Boar Infected with Virulent and Attenuated Isolates

Vaccines, 2020
Since the reappearance of African swine fever virus (ASFV), the disease has spread in an unprecedented animal pandemic in Eurasia. ASF currently constitutes the greatest global problem for the swine industry.
Aleksandra Kosowska, Estefanía Cadenas-Fernández, Sandra Barroso, Jose M. Sánchez-Vizcaíno, Jose A. Barasona   +4 more
doaj   +1 more source

Public health surveillance for mental health.

Preventing chronic disease, 2010
Public health systems have relied on public health surveillance to plan health programs, and extensive surveillance systems exist for health behaviors and chronic disease. Mental health has used a separate data collection system that emphasizes measurement of disease prevalence and health care use.
Elsie J. Freeman, MD, MPH, Lisa J. Colpe, PhD, MPH, Tara W. Strine, MPH, Satvinder Dhingra, Lisa C. McGuire, PhD, Laurie D. Elam-Evans, PhD, MPH, Geraldine S. Perry, DrPH, RD   +6 more
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source