Results 81 to 90 of about 9,860,066 (398)

Evidence in Practice – A Pilot Study Leveraging Companion Animal and Equine Health Data from Primary Care Veterinary Clinics in New Zealand [PDF]

, 2016
Veterinary practitioners have extensive knowledge of animal health from their day-to-day observations of clinical patients. There have been several recent initiatives to capture these data from electronic medical records for use in national surveillance ...
Amezcua, Buckland, Carroll, Chaudhry, Core Team R, Crump, Dórea, Henning, Jones, Kao, Kass, Kearsley-Fleet, Klompas, Lanyon, Li, Lund, Mateus, Mattin, Moore, Muellner, O’Neill, O’Neill, O’Neill, O’Neill, O’Neill, Pfeiffer, Radford, Reeder, Robertson, Robinson, Rogers, Sawford, Spackman, Summers, Sánchez-Vizcaíno, Venom Coding Group, Vourc’h, Wang, Ward, WHO, Wohlfender-Remy, Zurbrigg   +41 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Quality assessment of malaria microscopic diagnosis at the Aristide Le Dantec University Hospital of Dakar, Senegal, in 2020

BMC Research Notes
Background Following WHO guidelines, microscopy is the gold standard for malaria diagnosis in endemic countries. The Parasitology-Mycology laboratory (LPM) is the National Reference Laboratory and is currently undergoing ISO 15189 accreditation.
Mamane N. Garba, Awa B. Dème, Khadim Diongue, Younousse Diédhiou, Amadou M. Mbaye, NDèye M. Dia, N’Dèye A. Seck, Daba Zoumarou, Lamine Ndiaye, Mamadou S. Yade, Baba Dièye, Aita Sène, Abdoulaye Tine, Mariama Touré, Nogaye Gadiaga, Awa Fall, Bassirou Ngom, Djiby Sow, Aliou Ndiaye, Astou Keita, Mame F. Ndiaye, Jules F. Gomis, Nana F. Diop, Guète Diallo, Ibrahima M. Ndiaye, Elhadj M. Ba, Omar Bitèye, Cheikh Ndiaye, Fama S. D. Mbodji, Pape O. Ndiaye, Tolla Ndiaye, Amy Gaye, Mouhamad Sy, Yaye D. Ndiaye, Mame C. Seck, Mouhamadou Ndiaye, Aida S. Badiane, Mamadou A. Diallo, Daouda Ndiaye   +38 more
doaj   +1 more source

Syndromic surveillance of influenza-like illness in Scotland during the influenza A H1N1v pandemic and beyond [PDF]

, 2012
Syndromic surveillance refers to the rapid monitoring of syndromic data to highlight and follow outbreaks of infectious diseases, increasing situational awareness.
Box, Buckeridge, Burkom, Centers for Disease Control Working Group, Elliot, Elliot, Farrington, Farrington, Fleischauer, General Register Office for Scotland, Health Protection Agency and Health Protection Scotland, Health Protection Scotland, Health Protection Scotland, Health Protection Scotland, Health Protection Scotland, Heffernan, Holt, Jones, Meyer, R Development Core Team, Robertson, Scottish Government, Scottish Government, Scottish Government, Scottish Government, Scottish Government, Scottish Government, Scottish Government, Scottish Government, Scottish Television, Shmueli, Smith, Sonesson, Unkel, van den Wijngaard, Winters   +35 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Advancing global health equity: the transformative potential of community-based surveillance in developing countries [PDF]

, 2023
Juan S. Izquierdo‐Condoy, Andrea Tello-De-la-Torre, Patricio Espinosa Del Pozo, Esteban Ortiz‐Prado   +3 more
openalex   +1 more source

The RISKSUR EVA tool (Survtool): A tool for the integrated evaluation of animal health surveillance systems.

Preventive Veterinary Medicine, 2019
Information about infectious diseases at the global level relies on effective, efficient and sustainable national and international surveillance systems.
M. Peyre, L. Hoinville, James Njoroge, A. Cameron, D. Traon, F. Goutard, C. Calba, V. Grosbois, A. Delabouglise, Viktor Varant, J. Drewe, D. Pfeiffer, B. Häsler   +12 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The real-time infection hospitalisation and fatality risk across the COVID-19 pandemic in England

Nature Communications
The COVID-19 pandemic led to 231,841 deaths and 940,243 hospitalisations in England, by the end of March 2023. This paper calculates the real-time infection hospitalisation risk (IHR) and infection fatality risk (IFR) using the Office for National ...
Thomas Ward, Martyn Fyles, Alex Glaser, Robert S. Paton, William Ferguson, Christopher E. Overton   +5 more
doaj   +1 more source

General practice patients treated for substance use problems: a cross-national observational study in Belgium

BMC Public Health, 2016
Background General Practitioners (GPs) are well placed to care for patients with (chronic) substance use problems. This pilot was carried out to study the feasibility and usefulness of a continuous surveillance of substance use problems among general ...
Nicole Boffin, Jerome Antoine, Sarah Moreels, Simeon Wanyama, Karin De Ridder, Lieve Peremans, Marc Vanmeerbeek, Viviane Van Casteren   +7 more
doaj   +1 more source