Results 121 to 130 of about 2,121,296 (312)

Water, sanitation and children's health : evidence from 172 DHS surveys [PDF]

This paper combines 172 Demography and Health Survey data sets from 70 countries to estimate the effect of water and sanitation on child mortality and morbidity.
Fink, Gunther, Gunther, Isabel
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Online research methods: An interview with Dr Neil Coulson [PDF]

, 2014
Dr Neil Coulson, Associate Professor in Health Psychology at the University of Nottingham, is at the forefront of online research methods. His primary research explore the role of online support communities, online surveys, and the role of social ...
Williams, Sophie
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Early Detection of Chronic Kidney Disease in Mexico, a Case for Policy Transfer

Risk Management and Healthcare Policy
Rosalia Estephanie Mejia-Avila,1,* Ofelia Poblano-Verástegui,2,* Juan Alfredo Tamayo y Orozco,3,* Alfonso M Cueto-Manzano,4,* Emanuel Orozco Núñez2,* 1School of Public Health of Mexico, Cuernavaca, Morelos, Mexico;
Mejia-Avila RE, Poblano-Verástegui O, Tamayo y Orozco JA, Cueto-Manzano AM, Orozco Núñez E   +4 more
doaj  

Ethnicity, Immigration and Cancer Screening: Evidence for Canadian Women [PDF]

Introduction: Canada's annual immigrant intake is increasingly composed of visible minorities, with 59% of immigrants arriving in 1996-01 coming from Asia.
James Ted McDonald, Steven Kennedy
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cherokee Indian Health Survey [PDF]

Public Health Reports (1896-1970), 1956
openaire   +2 more sources

Centering Health Equity in Population Health Surveys [PDF]

JAMA Health Forum, 2020
openaire   +2 more sources