Results 71 to 80 of about 3,109,232 (307)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Health Systems: The Next Generation Welcome Address 2016
, 2016 Presented at the 1st forum on Health Systems: The Next Generation, September 16, 2016, Technology Square Research Building Georgia Tech, Atlanta, GA.Welcome Address by event organizers : Pinar Keskinocak, PhD, William W.
Keskinocak, Pinar, Swann, Julie
core
An Analysis of Geriatric Medicine in Malaysia-Riding the Wave of Political Change
Geriatrics, 2018 Malaysia became the centre of international attention when it democratically removed a semi-authoritarian government of 62 years during its 14th general election this year.
Maw Pin Tan +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Strong health systems are learning health systems
PLOS Global Public Health, 2022 Kabir Sheikh, Seye Abimbola
openaire +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Saúde e SociedadeResumo O crescente fluxo de imigração venezuelana provocou discussões acerca da inserção dessa comunidade no território brasileiro. Atualmente, o sistema de saúde roraimense tem o desafio de efetivar a universalização do acesso à saúde ao imigrante. Logo,
Loeste de Arruda-Barbosa +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development. [PDF]
, 2012 In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the challenges to developing such ...
Wyss K. +101 more
core +1 more source