Results 81 to 90 of about 3,109,232 (307)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Health Systems: The Next Generation - Panel 2: Educating the Next Generation in Health Systems

open access: yes, 2016
Presented at the 1st forum on Health Systems: The Next Generation, September 16, 2016, Technology Square Research Building Georgia Tech, Atlanta, GA.Panel 2: Educating the Next Generation in Health Systems was moderated by Bill Todd, Professor in the ...
Grace, Thomas   +4 more
core  

The impact of governance in primary health care delivery: a systems thinking approach with a European panel [PDF]

open access: yes, 2019
Enhancing primary health care (PHC) is considered a policy priority for health systems strengthening due to PHC’s ability to provide accessible and continuous care and manage multimorbidity.
Marti, Joachim   +7 more
core   +1 more source

Leading for Sustainable Health Systems

open access: yes, 2023
A sustainable health system is a cornerstone of any developing society, ensuring the well-being of its citizens and fostering economic development and growth.
Avery, M, Avery, Mark
core   +1 more source

The global cost of eliminating avoidable blindness

open access: yesIndian Journal of Ophthalmology, 2012
Aims : To complete an initial estimate of the global cost of eliminating avoidable blindness, including the investment required to build ongoing primary and secondary health care systems, as well as to eliminate the ′backlog′ of avoidable blindness. This
Kirsten L Armstrong   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Health Literacy: Improving Health, Health Systems, and Health Policy Around the World - Workshop Summary [PDF]

open access: yes, 2013
http://iom.edu/Reports/2013/Health-Literacy-Improving-Health-Health-Systems-and-Health-Policy-Around-the-World.aspx?utm_medium=etmail&utm_source=Institute%20of%20Medicine&utm_campaign=07.12.13+New+Report+-+Health+Literacy&utm_content ...
Hernandez, Lyla M.
core   +1 more source

Integrated mapping of local mental health systems in Central Chile

open access: yesRevista Panamericana de Salud Pública, 2018
Objective. To describe the availability of local mental health (MH) services in small MH catchment areas in Central Chile, using a bottom-up approach. Methods.
Jose A. Salinas-Perez   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Kazakhstan: health system review

open access: yes, 2012
xx, 154 p.Since becoming independent, Kazakhstan has undertaken major efforts in reforming its post-Soviet health system. Two comprehensive reform programmes were developed in the 2000s: the National Programme for Health Care and Development 2005–2010 ...
Rechel, Bernd   +5 more
core  

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