Results 91 to 100 of about 3,109,232 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lithuania: health system review

open access: yes, 2013
150 p.This analysis of the Lithuanian health system reviews the developmentsin organization and governance, health financing, health care provision,health reforms and health system performance since 2000.
Janoniene, Raimonda   +6 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Global health initiative investments and health systems strengthening : a content analysis of global fund investments [PDF]

open access: yes, 2013
Millions of dollars are invested annually under the umbrella of national health systems strengthening. Global health initiatives provide funding for low- and middle-income countries through disease-oriented programmes while maintaining that the ...
Atun, Rifat   +10 more
core   +1 more source

Implementation of Clinical Services for Adults with Obesity in Different Health Systems: A Scoping Review and Causal Loop Diagram

open access: yesDiabetes, Metabolic Syndrome and Obesity
Yan Xue,1 Menghuan Song,1,2 Honho Yu,3 Xianwen Chen,1 Carolina Oi Lam Ung,1,2,4 Hao Hu1,2,4 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, People’s Republic of China ...
Xue Y   +5 more
doaj  

Changes in the public health infrastructure in Poland in the context of an aging population

open access: yesJournal of Education, Health and Sport, 2018
The problem of an aging society, particularly the health situation of a group of older people is a challenge for health care for the coming years. Poland among other EU member states has one of the lowest (1) share of the population aged 65 years and ...
Monika Pajewska   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ohio State Office of Rural Health update

open access: yes, 2009
Electronic coverage as of Sept. 23, 2011: Winter 2008/2009-; No issues available for: Spring 2009, Summer 2009.; Combined issues for: Fall/Winter 2009, Spring/Summer 2011.; Vol. for Summer 2010- issued by Ohio Dept.
Ohio. State Office of Rural Health.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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