Results 101 to 110 of about 205,504 (307)

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

From Mexico to Mali: progress in health policy and systems research.

, 2008
In 2004, the ministerial summit in Mexico drew attention to the historic neglect of health policy and systems research (HPSR) and called for increased funding, investment in national institutional capacity for HPSR, and resources for selected priority ...
Evans, Tim, Alliance STAC, Ranson, Kent, Mills, Anne, Zarowsky, Christina, Bennett, Sara, Tangcharoensathien, Viroj, Adam, Taghreed   +7 more
core   +1 more source

Influence of health systems in malaria case management as part of malaria control in Tanzania [PDF]

, 2013
The World Health Organization report in 2007, declared that, it will not be possible to achieve national and international health goals without greater investments in health systems.
Masanja, Irene M.
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Factors influencing the work efficiency of district health managers in low-resource settings : a qualitative study in Ghana [PDF]

, 2016
There is increasing evidence that good district management practices can improve health system performance and conversely, that poor and inefficient management practices have detrimental effects.
Akweongo, Patricia, Aikins, Moses, Marc Bonenberger, Moses Aikins, Kaspar Wyss, Bonenberger, Marc, Patricia Akweongo, Wyss, Kaspar   +7 more
core   +1 more source

Barriers and enhancers to COVID-19 vaccination among healthcare workers in Zimbabwe

Journal of Public Health in Africa
Background: Coronavirus disease 2019 (COVID-19) vaccination is crucial for healthcare workers (HCWs). Understanding their vaccine uptake and perceptions is vital to promote acceptance. Aim: This study assessed COVID-19 vaccine uptake, associated factors
Nicholas Midzi, Clara Haruzivishe, Senga Sembuche, Masceline J. Mutsaka-Makuvaza, Rodgers Ayebare, Leah Mbabazi, Suzan Nakasendwa, Tonny Muwonge, Carl Mateta, Tafadzwa Madanhire, Cynthia Chaibva, Calleta Gwatiringa, Kudzaishe Mutsaka, Virginia Mawerewere, Isaac Phiri, Elizabeth Gonese, Tamrat Shaweno, Nebiyu Dereje, Raji Tajudeen, Mosoka Fallah, Munyaradzi Dobbie   +20 more
doaj   +1 more source

Health Systems Approach to Strengthen Rehabilitation

Acta Medica Philippina
Rehabilitation has been identified by the World Health Organization (WHO) as one of the key components in achieving Sustainable Development Goal (SDG) 3: “Ensure healthy lives and promote well-being for all at all ages”. Universal health coverage, as the main strategy to attain SDG 3, entails the provision of promotive, preventive, curative ...
openaire   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source