Results 71 to 80 of about 205,504 (307)

The Last Mile: Addressing India's Immunization Gap with Zero-Dose Insights from WUENIC Estimates

National Journal of Community Medicine
The global Immunization Agenda 2030, endorsed by the World Health Assembly in 2020, calls for a concentrated push to reach zero-dose children in all countries.
Palak Badhwar, Bhupender Singh Khanuja, Kapil Singh, Ashwani Verma   +3 more
doaj   +1 more source

Framing rehabilitation through health policy and systems research: priorities for strengthening rehabilitation

Health Research Policy and Systems, 2022
Background Recent estimates report that 2.4 billion people with health conditions globally could benefit from rehabilitation. While the benefits of rehabilitation for individuals and society have been described in the literature, many individuals ...
Alarcos Cieza, Aku Kwamie, Qhayiya Magaqa, Nino Paichadze, Carla Sabariego, Karl Blanchet, Nukhba Zia, Abdulgafoor M. Bachani, Abdul Ghaffar, Bente Mikkelsen   +9 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Complex interventions in complex systems : health systems analysis of antiretroviral treatment scaleup in Burkina Faso, Tanzania and Uganda [PDF]

, 2012
Background: Antiretroviral treatment (ART) is the most complex health intervention ever taken to scale in low-income countries and will remain largely dependent on external funding in the future.
Windisch, Ricarda
core   +1 more source

Identifying and costing common gaps in Central and West Africa pharmaceutical regulation

Frontiers in Medicine
BackgroundRegulatory systems strengthening is crucial for catalyzing access to safe and effective medical products and health technologies (MPHT) for all. Identifying and addressing common regulatory gaps through regional approaches could be instrumental
Claudia P. Alfonso, Guy B. N’Jambong, Guy B. N’Jambong, Alaa Magdy, Laura Di Trapani, Rutendo Kuwana, Abraham G. Kahsay, Diadié Maïga, Sybil N. A. Ossei-Agyeman-Yeboah, Aimé B. Djitafo Fah, Margareth Ndomondo-Sigonda   +10 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Comparison of Medicine Availability Measurements at Health Facilities: Evidence from Service Provision Assessment Surveys in Five Sub-Saharan African Countries. [PDF]

, 2013
With growing emphasis on health systems strengthening in global health, various health facility assessment methods have been used increasingly to measure medicine and commodity availability.
Choi, Yoonjoung, Ametepi, Paul
core   +1 more source

The quality of free antenatal and delivery services in Northern Sierra Leone

Health Research Policy and Systems, 2017
Background The number of maternal deaths in sub-Saharan Africa continues to be overwhelmingly high. In West Africa, Sierra Leone leads the list, with the highest maternal mortality ratio.
Manso M. Koroma, Samuel S. Kamara, Evelyn A. Bangura, Mohamed A. Kamara, Virgil Lokossou, Namoudou Keita   +5 more
doaj   +1 more source

WOmen's Action for Mums and Bubs (WOMB) Trial Protocol: A Non-randomized Stepped Wedge Implementation Trial of Participatory Women's Groups to Improve the Health of Aboriginal and Torres Strait Islander Mothers and Children in Australia

Frontiers in Public Health, 2020
Introduction: In Australia, there have been improvements in Aboriginal and Torres Strait Islander maternal health, however inequities remain. There is increasing international evidence illustrating the effectiveness of Participatory Women's Groups (PWGs)
Karen Carlisle, Karen Carlisle, Karen Carlisle, Catrina Felton-Busch, Catrina Felton-Busch, Catrina Felton-Busch, Yvonne Cadet-James, Yvonne Cadet-James, Yvonne Cadet-James, Judy Taylor, Judy Taylor, Judy Taylor, Ross Bailie, Jane Farmer, Megan Passey, Veronica Matthews, Emily Callander, Rebecca Evans, Rebecca Evans, Rebecca Evans, Janet Kelly, Robyn Preston, Michelle Redman-MacLaren, Michelle Redman-MacLaren, Michelle Redman-MacLaren, Haylee Fox, Adrian Esterman, Merrick Zwarenstein, Sarah Larkins, Sarah Larkins, Sarah Larkins   +30 more
doaj   +1 more source