Results 101 to 110 of about 17,104,065 (353)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Rising health spending, new medical technology and the Baumol effect [PDF]

open access: yes
This paper estimates the Baumol effect in health spending, using a panel data set of OECD countries. Health expenditure as a share of GDP rises in most OECD countries.
Marc Pomp, Suncica Vujic
core  

mHealth in China and the United States: How Mobile Technology is Transforming Healthcare in the World's Two Largest Economies [PDF]

open access: yes, 2014
In this paper, we explore ways mobile technology can help with these difficulties. Specifically, we look at avenues through which mobile devices boost productivity, aid communications, and help providers improve affordability, access, and treatment ...
Darrell West   +11 more
core  

The role of technology in music listening for health and wellbeing [PDF]

open access: yes, 2015
There is growing evidence that listening to music can have significant effects upon health and wellbeing. This article briefly summarises research examining the effects of music listening on a variety of health parameters, and explores the potential role
Knox, Don, MacDonald, Raymond
core   +2 more sources

Emerging Use of Early Health Technology Assessment in Medical Product Development: A Scoping Review of the Literature

open access: yesPharmacoEconomics (Auckland), 2017
Early health technology assessment is increasingly being used to support health economic evidence development during early stages of clinical research.
Maarten J. IJzerman   +3 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Towards a Unified European View of Clinical Evidence: What ‘Health Technology Assessment Organizations’ Can Learn from Regulatory Experience

open access: yesJournal of Market Access & Health Policy
The harmonization of pharmaceutical regulations within the European Union has been a crucial step towards ensuring high safety standards and efficient access to innovative medicines.
Karl Broich, Wiebke Löbker
doaj   +1 more source

Connected Healthcare System Technology Interventions to Improve Patient Safety by Reducing Medical Errors: A Systematic Review [PDF]

open access: yesGlobal Journal on Quality and Safety in Healthcare
Medication or medical mistakes, the third highest cause of death in the United States, occur from prescription writing to administering the therapy, with serious clinical and cost repercussions.
Ramkrishna Mondal, Mohammed Sameer
doaj   +1 more source

HITECH Revisited [PDF]

open access: yes, 2010
Assesses the 2009 Health Information Technology for Economic and Clinical Health Act, which offers incentives to adopt and meaningfully use electronic health records.
Helen R. Pfister   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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