Results 151 to 160 of about 2,763,321 (346)

Effectiveness and safety of biological and target synthetic drugs treatment for psoriatic arthritis: a systematic review with network meta-analysis

Advances in Rheumatology
Background Psoriatic arthritis (PA) is a chronic inflammatory systemic arthritis that can result in loss of functional capacity and joint deformation. This systematic review assessed the effectiveness and safety of biological and target synthetic drugs ...
Thais Montezuma, Livia Fernandes Probst, Matheus Oliveira Almeida   +2 more
doaj   +1 more source

Common Problems, Common Data Model Solutions: Evidence Generation for Health Technology Assessment [PDF]

, 2020
Seamus Kent, Edward Burn, Dalia Dawoud, Páll Jónsson, Jens Torup Østby, Nigel Hughes, Peter R. Rijnbeek, Jacoline C. Bouvy   +7 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Internal evaluation of the European network for Health Technology Assessment project [PDF]

, 2009
Lise Lund Håheim, Iñaki Imaz-Iglesia, Marlène Läubli Loud, Teresa Gasparetto, Jesús González-Enríquez, Helena Dahlgren, Igor Trofimovs, Elena Berti, Berit Mørland   +8 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Correction: A systematic literature review of economic evaluation studies of interventions impacting antimicrobial resistance

Antimicrobial Resistance and Infection Control, 2023
Chris Painter, Dian Faradiba, Kinanti Khansa Chavarina, Ella Nanda Sari, Yot Teerawattananon, Kristina Aluzaite, Aparna Ananthakrishnan   +6 more
doaj   +1 more source

A systematic review on reporting quality of economic evaluations for negotiated glucose-lowering drugs in China national reimbursement drug list

BMC Health Services Research
Background This study aimed to examine the reporting quality of existing economic evaluations for negotiated glucose-lowering drugs (GLDs) included in China National Reimbursement Drug List (NRDL) using the Consolidated Health Economic Evaluation ...
Shi-Yi Bao, Liu Liu, Fu-Ming Li, Yi Yang, Yan Wei, Hui Shao, Jian Ming, Jun-Tao Yan, Ying-Yao Chen   +8 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

PD196 The Importance Of Promoting The Culture Of Health Technology Assessment Among Healthcare Professionals [PDF]

Laura Llinàs-Mallol, Berta Mestre-Lleixà, Rosa Maria Vivanco‐Hidalgo   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source