Results 141 to 150 of about 23,885,267 (262)

Quarterly Report to the Technology Assessment Board, July 1 - September 30, 1980

open access: yes, 1980
This is a quarterly report detailing the budget and progress of the Office of Technology ...
Office of Technology Assessment
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Quarterly Report to the Technology Assessment Board, January 1 - March 31, 1980

open access: yes, 1980
This is a quarterly report detailing the budget and progress of the Office of Technology ...
Office of Technology Assessment
core  

Surrogate endpoints in cost-effectiveness analysis for use in health technology assessment - a qualitative analysis. [PDF]

open access: yesInt J Technol Assess Health Care
Flight L   +7 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Quarterly Report to the Technology Assessment Board, October 1 - December 31, 1990

open access: yes, 1991
This is a quarterly report detailing the budget and progress of the Office of Technology ...
Office of Technology Assessment
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Quarterly Report to the Technology Assessment Board, January 1 - March 31, 1987

open access: yes, 1987
Quarterly report to the Technology Assessment Board, detailing progress and budgets at ...
Office of Technology Assessment
core  

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