Results 121 to 130 of about 979,842 (317)
Health technology assessment in Singapore [PDF]
International Journal of Technology Assessment in Health Care, 2009 The Republic of Singapore is an island city-state in Southeast Asia. Its population enjoys good health and the Singapore Ministry of Health's mission is to promote good health and reduce illness, ensure access to good and affordable health care, and pursue medical excellence.
openaire +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Technical memoranda (United States. Congress. Office of Technology Assessment)
, 1979 A study by the Office of Technology Assessment (OTA) that "analyzes the arguments for and against NLM's (National Library of Medicine) creation and dissemination of health-related bibliographic information" and "provides information designed to help ...
United States. Congress. Office of Technology Assessment.
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Health Technology Case Study 30: The Market for Wheelchairs: Innovations and Federal Policy [PDF]
, 1984 An assessment by the Office of Technology Assessment (OTA) that "focuses on how Federal Government policies affect innovations in wheelchair characteristics" (p. 3)
United States. Congress. Office of Technology Assessment.
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Informing a decision framework for when NICE should recommend the use of health technologies only in the context of an appropriately designed programme of evidence development [PDF]
, 2012 © Queen’s Printer and Controller of HMSO 2012. This work was produced by Claxton et al. under the terms of a commissioning contract issued by the Secretary of State for Health.Background: The general issue of balancing the value of evidence about the ...
M Soares +17 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
BMC Public Health, 2017 Background A recent recalibration of the ONCOTYROL Prostate Cancer Outcome and Policy (PCOP) Model, assuming that latent prostate cancer (PCa) detectable at autopsy might be detectable by screening as well, resulted in considerable worsening of the ...
Nikolai Mühlberger +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 1993 The following is the first comprehensive listing of health technology research projects ongoing in British Columbia since 1988. The B.C. Office of Health Technology Assessment's (BCOHTA) Steering Committee approved the compilation of this project to ...
British Columbia Office of Health Technology Assessment
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source