Results 121 to 130 of about 2,804,815 (317)
Optimal scheduling of reliability development activities [PDF]
, 2004 Probabilistic Safety Assessment and Management is a collection of papers presented at the PSAM 7 - ESREL '04 Conference in June 2004. The joint Conference provided a forum for the presentation of the latest developments in methodology and application of ...
Johnston, W., Quigley, J.L., Walls, L.A.
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Networked Living: a new approach to teaching introductory ICT [PDF]
, 2006 The course T175 Networked Living is a 300 hour, multiple media, distance learning course offered by the UK Open University. The first presentation of the course, in 2005, attracted over 1600 students.
Bissell, Christopher, Kear, Karen
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Using health technology assessment to assess the value of new medicines: results of a systematic review and expert consultation across eight European countries [PDF]
, 2017 Although health technology assessment (HTA) systems base their decision making process either on economic evaluations or comparative clinical benefit assessment, a central aim of recent approaches to value measurement, including value based assessment ...
Angelis, Aris +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Assessment of the learning curve in health technologies: a systematic review [PDF]
, 2000 Objective: We reviewed and appraised the methods by which the issue of the learning curve has been addressed during health technology assessment in the past.
Garthwaite, Paul H. +5 more
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Systematic Reviews, 2019 Background Cataract is the leading cause of blindness and low vision worldwide. Presently, cataract surgery is the only treatment for cataract and is very effective in restoring sight. In cataract surgery, the natural lens of the eye that becomes clouded
Shalu Jain +4 more
doaj +1 more source
Surplus Appropriation from R&D and Health Care Technology Assessment Procedures [PDF]
Given the rapid growth in health care spending that is often attributed to technological change, many private and public institutions are grappling with how to best assess and adopt new health care technologies.
Anupam B. Jena, Tomas J. Philipson
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