Results 111 to 120 of about 979,842 (317)
BMC Cancer, 2017 Background Due to high survival rates and the relatively small benefit of adjuvant therapy, the application of personalized medicine (PM) through risk stratification is particularly beneficial in early breast cancer (BC) to avoid unnecessary harms from ...
Beate Jahn +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 1983 A case study by the Office of Technology Assessment (OTA) that examines "the evidence on variations in lengths of hospital stay and their relation to health outcomes" (p. 3)
United States. Congress. Office of Technology Assessment.
core
Health Technology Case Study 29: The Boston Elbow [PDF]
, 1984 A case study by the Office of Technology Assessment (OTA) that "focuses on amputees and the social policies that bear on their use of the Boston Elbow" (p. 3)
United States. Congress. Office of Technology Assessment.
core
Transparency in health technology assessments [PDF]
BMJ, 2007 The running battle over which National Health Service patients with dementia should have access to the dementia drug donepezil (Aricept) is to progress to the courts. Last year, guidance from the National Institute for Health and Clinical Excellence (NICE) restricted use of the drug to patients with moderate and severe Alzheimer's disease, thereby ...
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Resource allocation and health technology assessment in Australia: Views from the local level [PDF]
, 2009 Objectives: Several studies have shown that a key determinant of successful health technology assessment (HTA) uptake is a clear, fair, and consistent decision-making process for the approval and introduction of health technologies. The aim of this study
Van Gool, K +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Selected Topics in Federal Health Statistics [PDF]
, 1979 A study by the Office of Technology Assessment (OTA) that looks at how information about Federal health programs is collected. Part 1 "inventories the different health data collection systems administered by the Department of Health, Education, and ...
United States. Congress. Office of Technology Assessment.
core
Discover OncologyObjective Examining the distribution of breast cancer (BC) stage and molecular subtype among women aged below ( 65 years) the recommended screening age range helps to understand the screening program's characteristics and contributes to enhancing the ...
Judit Tittmann +7 more
doaj +1 more source