Results 71 to 80 of about 2,763,321 (346)

Role of the Patient‘s Viewpoint in Health Technologies Assessment in Bulgaria [PDF]

, 2021
C. Georgieva, Antoniya Yanakieva
openalex   +1 more source

Early surgery versus initial conservative treatment in patients with traumatic intracerebral haemorrhage [STITCH(Trauma)] : the first randomized trial [PDF]

, 2015
Acknowledgements This project was funded by the NIHR Health Technology Assessment programme (project number 07/37/16). The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the HTA programme, NIHR, NHS ...
A. David Mendelow, Andreas Unterberg, Barbara A. Gregson, Dwayne Boyers, Elaine McColl, Elise N. Rowan, Iain R. Chambers, null null, Patrick M. Mitchell, Paul McNamee, Richard Francis   +10 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Comparative analysis of breast cancer care models and patient journeys across six European countries: implications for the Austrian healthcare system

BMC Health Services Research
Introduction The increasing prevalence of breast cancer is straining hospital-centred healthcare systems worldwide, including Austria’s. This study examined breast cancer care models across six European countries to identify alternative approaches for ...
Nicole Grössmann-Waniek, Michaela Riegelnegg, Claudia Wild, Christoph Strohmaier   +3 more
doaj   +1 more source

Lipoedema research priorities: a Swedish priority-setting partnership for future treatment and diagnostic studies

BMJ Open
Objectives To identify research priorities related to the diagnosis, treatment and management of lipoedema.Design This was a research question priority-setting that ensured the involvement of patients, relatives and healthcare professionals in all parts.
Sara Fundell, Johan Dahlberg, Marie Österberg, Christel Hellberg, Jenny Stenman, Åsa G Andersson, Silvia Edling, Anders Liss   +7 more
doaj   +1 more source

Comparative Effectiveness and Safety of Allografts and Autografts in Posterior Cruciate Ligament Reconstruction Surgery: A Systematic Review

Arthroscopy, Sports Medicine, and Rehabilitation, 2020
Purpose: To evaluate the evidence of the effectiveness and safety of allografts compared to autografts in posterior cruciate ligament reconstruction.
Cecilia de Villiers, M.Sc., B.Sc., Gregor Goetz, M.S.Sc., M.P.H., Patrick Sadoghi, M.D., Ph.D., M.B.A., Sabine Geiger-Gritsch, D.M.Sc., M.H.Sc., M.Pharm   +3 more
doaj   +1 more source

Mapping of health technology assessment in selected countries [PDF]

, 2013
Objectives: The aim of this study was to develop and apply an instrument to map the level of health technology assessment (HTA) development at country level in selected countries.
Banta, D., Broos, P., Oortwijn, W., Todorova, L., Vondeling, H.   +4 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Information Graphics in Health Technology Assessment [PDF]

, 2013
This thesis addresses the question of the design, production and use of information graphics in health technology assessment (HTA). Drawing on previous research in both information design and health policy, it describes a comprehensive design process for
Stahl-Timmins, William Marck
core