Results 81 to 90 of about 2,763,321 (346)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Study protocol: HepaT1ca - an observational clinical cohort study to quantify liver health in surgical candidates for liver malignancies. [PDF]
, 2018 Background Accurate assessment of liver health prior to undertaking resectional liver surgery or chemoembolisation for primary and secondary cancers is essential for patient safety and optimal outcomes.
A Abulkhir +28 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
BMC Medicine, 2023 Background Although non-pharmacological smoking cessation measures have been widely used among smokers, current research evidence on the effects of smoking cessation is inconsistent and of mixed quality.
Tao Nian +11 more
doaj +1 more source
Coverage with evidence development: applications and issues [PDF]
, 2010 Copyright © Cambridge University Press, 2010OBJECTIVES: The aim of this study was to describe the current issues surrounding Coverage with Evidence Development (CED).
Chalkidou +4 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Clinical Governance: An International Journal, 2006 Health technology assessment (HTA) involves the systematic evaluation of healthcare technologies and the dissemination of assessment findings. Its main purpose is to provide objective information to support healthcare decisions and policy-making. This article provides a brief overview of HTA, covering availability of assessment reports, approaches used,
openaire +3 more sources
Telemedicine Utilization in Tertiary, Specialized, and Secondary Hospitals in Thailand
Telemedicine ReportsIntroduction: COVID-19 has accelerated the adoption of telemedicine for counseling, follow-up examination, and treatment purposes. The official guidelines in Thailand were launched to regulate or frame the protocols for health care professions and teams ...
Piyada Gaewkhiew +10 more
doaj +1 more source
OP120 Developing A Call To Action For Patient Involvement In Health Technology Assessment (HTA) In Southern Africa [PDF]
, 2023 Lauren Pretorius +2 more
openalex +1 more source
Assessment of the learning curve in health technologies: a systematic review [PDF]
, 2000 Objective: We reviewed and appraised the methods by which the issue of the learning curve has been addressed during health technology assessment in the past.
Garthwaite, Paul H. +5 more
core +2 more sources