Results 161 to 170 of about 10,030,185 (350)

Exponential Health Utility: A Characterization and Comments on a Paper by Happich and Mühlbacher. [PDF]

In a recent paper Happich and Mühlbacher [Eur J Health Econom (2003) 4:292-294] proposed an axiom of constant absolute trade-off in life years, and studied the family of QALY models satisfying this axiom under expected utility and mutual utility ...
Lars Peter Østerdal
core  

Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire.

Journal of the American Medical Association (JAMA), 1999
R. Spitzer, K. Kroenke, Janet B W Williams   +2 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A systematic review and meta-analysis of health utility values among patients with ischemic stroke. [PDF]

Front Neurol, 2023
Zhou J, Wei Q, Hu H, Liu W, Guan X, Ma A, Wang L.   +6 more
europepmc   +1 more source

Estimating Quality of Life Decrements Due to Diabetes Complications in the United States: The Health Utility Index (HUI) Diabetes Complication Equation

PharmacoEconomics (Auckland), 2019
H. Shao, Shuang Yang, V. Fonseca, C. Stoecker, Lizheng Shi   +4 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cataloging health state utility estimates for Duchenne muscular dystrophy and related conditions

Health and Quality of Life Outcomes
Background Duchenne muscular dystrophy (DMD) is a genetic disease resulting in progressive muscle weakness, loss of ambulation, and cardiorespiratory complications. Direct estimation of health-related quality of life for patients with DMD is challenging,
Lauren A. Do, Lauren E. Sedita, Alexa C. Klimchak, Rachel Salazar, David D. Kim   +4 more
doaj   +1 more source

Equality of Opportunity and Optimal Cash and In-Kind Policies [PDF]

This paper examines the argument for public provision of certain private goods, like education and health, based on equality of opportunity by studying the utility possibility frontier of a society in which there is a concern for the distribution of ...
Leonardo Gasparini, Santiago Pinto
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Psychometric properties and comparison of four health utility approaches among myopia patients in China. [PDF]

Health Qual Life Outcomes, 2023
Dou L, Xu Y, Chen G, Li S.
europepmc   +1 more source