Results 61 to 70 of about 793,394 (367)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Why they come, why they stay and why they leave: a survey to understand the drivers of recruitment, retention, and attrition of allied health clinicians in an Australian metropolitan health network

BMC Health Services Research
Background While allied health plays a central role in healthcare, workforce challenges are straining the sector. Challenges are shaped by population changes, emerging models of care, and educational limitations, and were exacerbated by COVID-19.
Abby M. Foster, Simone Munro, Janet Golder, Debra Mitchell   +3 more
doaj   +1 more source

Implementing a health labour market analysis to address health workforce gaps in a rural region of India

Human Resources for Health, 2022
Background Human Resources for Health (HRH) are essential for making meaningful progress towards universal health coverage (UHC), but health systems in most of the developing countries continue to suffer from serious gaps in health workforce.
Samir Garg, Narayan Tripathi, Michelle McIsaac, Pascal Zurn, Tomas Zapata, Dilip S. Mairembam, Niharika Barik Singh, Hilde de Graeve   +7 more
doaj   +1 more source

Developing the mental health workforce capacity in primary care: implementing the role of graduate primary care mental health workers in England [PDF]

, 2007
The scale of current demand on primary care services from people seeking help with common mental health problems places enormous pressure on the existing front line workers in general practice.
Chadwick, Siobhan, James, Alison, Patel, Jit, Rushforth, David   +3 more
core   +1 more source

Imbalance in the health workforce [PDF]

Human Resources for Health, 2004
AbstractImbalance in the health workforce is a major concern in both developed and developing countries. It is a complex issue that encompasses a wide range of possible situations. This paper aims to contribute not only to a better understanding of the issues related to imbalance through a critical review of its definition and nature, but also to the ...
Stilwell Barbara, Dal Poz Mario R, Zurn Pascal, Adams Orvill   +3 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Strengthening Public Health Nursing Part I: Policies and Programs that Recognize Nursing's Role in Assuring the Public's Health [PDF]

, 2008
Highlights nurses' multifaceted contributions to public health and emergency response, profiles model public health programs led by their efforts, examines workforce issues nursing faces, and looks at promising federal and state policies to address ...

core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Health and Safety Issues of an Aging Workforce [PDF]

, 2019
[Excerpt] What do we mean by an “aging workforce”? As we live longer and healthier, older people continue to grow as a proportion of the working population. The number of workers of age 45 and older has doubled since 1950. Workers \u3e55 years of age are
Brown, Nellie J
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source