Results 81 to 90 of about 11,928,006 (258)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
BMC Health Services ResearchIntroduction The COVID-19 pandemic unveiled huge challenges in health workforce governance in the context of public health emergencies in Africa. Several countries applied several measures to ensure access to qualified and skilled health workers to ...
Adam Ahmat +6 more
doaj +1 more source
The Health Workforce and Workforce Performance [PDF]
, 2003 Over the last ten years, performance management for health sector systems has received increased attention. In many countries privatisation, decentralisation, user involvement and cost containment have changed the structure and the functioning of health delivery dramatically. The role and performance of the workforce in the health sector has often been
openaire +1 more source
The aged care workforce 2012: final report [PDF]
, 2012 The Aged Care Workforce Census and Survey informs workforce planning on issues surrounding the recruitment and retention, training and education, carer development and employment conditions of the aged care workforce.
Debra King
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Journal of Multidisciplinary HealthcareLucy Whelan,1 Sharon L McLean,1 Alexandra Edwards,1,2 Sandra Glagovski,1,2 Jessica Huglin,1 Janet E Golder,1,3 Abby M Foster1,2,4 1Allied Health Workforce Innovation, Strategy, Education & Research (WISER) Unit, Monash Health, Melbourne, VIC ...
Whelan L +6 more
doaj
BMC Public HealthBackground Most studies examining COVID-19 related stigma in the healthcare setting have focused either on the patient’s or clinicians’ own experiences of being stigmatized.
Janice A. Sabin +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Global public health workforce [PDF]
Perspectives in Public Health, 2014 Welcome to this bumper issue of Perspectives where we consider public health from a global aspect. As the world population undergoes demographic, social, economic and epidemiological change, challenges facing each country in some cases are the same, but in some, they are specific and unique to that population.
openaire +2 more sources