Results 51 to 60 of about 783,612 (311)

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Healthcare-Associated Infections Among Neonates in Brazil [PDF]

, 2017
Objective: To describe the epidemiology of healthcare-associated infections (HAIs) among neonates. Design: Prospective surveillance of HAIs was conducted during 2 years.
Calil, Roseli, Costa, Maria Luiza M., Frota, Ana Cristina Cisne, Pessoa-Silva, Carmem Lúcia, Richtmann, Rosana, Santos, Rosana Maria Rangel, Wey, Sergio Barsanti   +6 more
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The relative importance of large problems far away versus small problems closer to home: insights into limiting the spread of antimicrobial resistance in England

BMC Medicine, 2017
Background To combat the spread of antimicrobial resistance (AMR), hospitals are advised to screen high-risk patients for carriage of antibiotic-resistant bacteria on admission.
Tjibbe Donker, Katherine L. Henderson, Katie L. Hopkins, Andrew R. Dodgson, Stephanie Thomas, Derrick W. Crook, Tim E. A. Peto, Alan P. Johnson, Neil Woodford, A. Sarah Walker, Julie V. Robotham   +10 more
doaj   +1 more source

Exploring what lies behind public preferences for avoiding health losses caused by lapses in healthcare safety and patient lifestyle choices [PDF]

, 2013
© 2013 Singh et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),which permits unrestricted use, distribution, and ...
A Bryman, Amanda Baine, C Green, E Nord, J Coast, J Ratcliffe, J Singh, Jeshika Singh, Joanne Lord, L Steuten, LJ Damschroder, Louise Longworth, Martin Buxton, NICE Citizens Council, P Dolan, P Dolan, R Baker, R Cookson, Shepley Orr, V Braun   +19 more
core   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Assessing the Bacterial Community Composition of Bivalve Mollusks Collected in Aquaculture Farms and Respective Susceptibility to Antibiotics

Antibiotics, 2021
Aquaculture is a growing sector, providing several products for human consumption, and it is therefore important to guarantee its quality and safety. This study aimed to contribute to the knowledge of bacterial composition of Crassostrea gigas, Mytilus ...
Vanessa Salgueiro, Lígia Reis, Eugénia Ferreira, Maria João Botelho, Vera Manageiro, Manuela Caniça   +5 more
doaj   +1 more source

Healthcare Associated Infections. educational intervention by "Adult Learning" in an Italian teaching hospital [PDF]

, 2016
An educational intervention for HAI prevention based on a combination of training, motivation and subsequent application in the current clinical practice in an Italian teaching ...
Berdini, S, De Luca, A, DI NINNO, Filippo, Ferretti, Filippo, Marani, Alessandra, Montesano, M, Napoli, Christian, Orioli, Riccardo, Orsi, Giovanni Battista, Petruccioli, M. C, Rinaldi, Alessandro, Tarsitani, Gianfranco   +11 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Assessing the improvement of healthcare workers’ alcohol-based hand rub with the Pulpe'Friction audit

GMS Hygiene and Infection Control
Hand hygiene is essential to prevent the transmission of pathogens between healthcare workers (HCWs) and patients. Launched in 2019, Pulpe’Friction is a declarative audit that provides a quick assessment of hand hygiene in healthcare facilities.
Daniel Verbouk, Muriel Péfau, Raymond Nasso, Pierre Parneix, Mélanie Ohanian, Fanny Velardo, Anne-Gaëlle Venier   +6 more
doaj   +1 more source