Results 121 to 130 of about 1,160,341 (307)

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

Advanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman, Lars Lau Raket, Michael Schöll, for the Alzheimer's Disease Neuroimaging Initiative†   +3 more
wiley   +1 more source

Is a No-Restraint Policy Associated with Increased Aggression Towards Healthcare Professionals Among Inpatient Psychiatric Units? A 16-Year Retrospective Observational Study Conducted in Italy

Nursing Reports
The aim of this study was to investigate aggression-related work accidents in an inpatient psychiatric unit before and after implementing a no-restraint policy in Italy.
Marco Colizzi, Carla Comacchio, Marco Garzitto, Giovanni Napoli, Chiara Battiston, Tatiana Tam, Marco Bertoli, Calogero Anzallo, Alvisa Palese, Matteo Balestrieri   +9 more
doaj   +1 more source

Barriers to wound debridement: Results of an online survey [PDF]

, 2016
This paper presents the results of an online survey which investigated healthcare professionals’ knowledge of wound debridement and the techniques used.
Ousey, Karen, Rippon, Mark, Stephenson, John   +2 more
core  

Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy

Advanced Science, EarlyView.
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang, Yangyang Guo, Guoping Xu, Luhaoxiang Liu, Lin Chen, Cai Zhang, Yiming Li, Jianmin Li, Yang Zhao   +8 more
wiley   +1 more source

Knowledge and attitudes towards sarcopenia among healthcare professionals

Annals, Academy of Medicine, Singapore
Sarcopenia is the age-related loss of skeletal muscle mass as well as muscle strength and/ or performance.1 Sarcopenia is an important public health issue as it has a significant impact on patient health outcomes, and personal and social economic ...
Jeremy Jun Wei Teng, Raymond Kai Heng Goh, Melanie Mei Ying Tan, Le Alicia How, Li Feng Tan   +4 more
doaj   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Prevalence and predictors of post-COVID-19-related symptoms: an extended follow-up among employees in health and welfare services in Germany: a short report

GMS Hygiene and Infection Control
Objective: To describe persistent symptoms after a work-related COVID-19 infection in health and welfare workers and the identification of predictors of these symptoms.
Koch, Peter, Steinke, Lara, Peters, Claudia, Nienhaus, Albert   +3 more
doaj   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

EPIDEMIOLOGICAL ANALYSIS OF TUBERCULOSIS CHARACTERISTICS AMONG HEALTHCARE WORKERS IN BRAZIL (2014–2025)

Brazilian Journal of Infectious Diseases
Introduction: Healthcare professionals (HPs) are at higher risk of exposure to and development of tuberculosis (TB). This study aims to outline the epidemiological profile of TB cases reported among healthcare professionals in Brazil between 2014 and ...
Mailla Mylena Mendes Bergmann, Leonardo Gonçalves Artoni, Josue Rulian Mendes Paneque, Roberto Carlos Cruz Carbonell, Joquebede de Lima Bezerra Carbonell, Kayla Nunes Paiva   +5 more
doaj   +1 more source