Results 51 to 60 of about 330,877 (312)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Hair tourniquet syndrome leading to nipple autoamputation in an adult female: a case report

Frontiers in Surgery
This is a unique case of hair thread tourniquet syndrome (HTTS) affecting the nipple of an adult female, leading to spontaneous autoamputation, a phenomenon rarely documented in the literature for this anatomical site.
Alaa A. Alshurafa, Alaa A. Alshurafa, Khaled Alshawwa, Khaled Alshawwa   +3 more
doaj   +1 more source

Difficulties facing healthcare workers in the era of AIDS treatment in Lesotho

SAHARA-J, 2016
Sub-Saharan Africa is most affected by the AIDS pandemic and Lesotho is no exception. In many countries, healthcare workers are at the forefront of the fight against AIDS.
Masebeo Veronica Koto, Pranitha Maharaj
doaj   +1 more source

Etiological explanation, treatability and preventability of childhood autism: a survey of Nigerian healthcare workers' opinion

Annals of General Psychiatry, 2009
Background Because of their peculiar sociocultural background, healthcare workers in sub-Saharan African subcultures may have various conceptions on different aspects of autism spectrum disorders (ASD), such as etiology, treatment and issues of prognosis.
Okonkwo Kevin O, Eaton Julian, Ebigbo Peter O, Agomoh Ahamefule O, Bakare Muideen, Onwukwe Jojo U, Onyeama Gabriel M   +6 more
doaj   +1 more source

Attitudes and intentions toward seeking professional psychological help among Chinese healthcare workers during the COVID-19 pandemic [PDF]

, 2023
Ruirui Huang, Xiaoyan Peng, Shuai Yu, Yumei Tian, Chuanying Gao   +4 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Drivers and mediators of healthcare workers’ anxiety in one of the most affected hospitals by COVID-19: a qualitative analysis

BMJ Open, 2021
Objective To report the driving and mediating factors of healthcare workers’ anxiety during the COVID-19 pandemic.Design Qualitative indepth interview study.Setting The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and
Tian Tian, Mengling Fang, Bo Xia, Yan Hao, Zhenghao Wu   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Anti–SARS-CoV Immunoglobulin G in Healthcare Workers, Guangzhou, China

Emerging Infectious Diseases, 2005
To determine the prevalence of inapparent infection with severe acute respiratory syndrome (SARS) among healthcare workers, we performed a serosurvey to test for immunoglobulin (Ig) G antibodies to the SARS coronavirus (SARS-CoV) among 1,147 healthcare ...
Wei-Qing Chen, Ci-Yong Lu, Tze-wai Wong, Wen-Hua Ling, Zhong-Ning Lin, Yuan-Tao Hao, Qing Liu, Ji-Qian Fang, Yun He, Fu-Tian Luo, Jin Jing, Li Ling, Xiang Ma, Yi-Min Liu, Gui-Hua Chen, Jian Huang, Yuan-Sen Jiang, Wen-Qi Jiang, He-Qun Zou, Guang-Mei Yan   +19 more
doaj   +1 more source

Meningococcal disease and healthcare workers

BMJ, 1999
Although Neisseria meningitidis is a relatively uncommon cause of overt infection (2580 notifications in 1998),1 the horrors of its clinical presentation have stimulated intense media interest, particularly after outbreaks. With the disappearance of many infectious competitors in the latter half of this century, meningococcal disease has become the ...
Pollard, A, Begg, N
openaire   +3 more sources