Results 181 to 190 of about 9,131,437 (364)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Healthy Brains Healthy Lives 2024 Symposium

McGill Journal of Medicine
Healthy Brains Healthy Lives (HBHL)
doaj   +1 more source

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI

Proc. Natl. Acad. Sci. USA, 2004
M. Greicius, G. Srivastava, A. Reiss, V. Menon   +3 more
semanticscholar   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

American College of Sports Medicine position stand. Progression models in resistance training for healthy adults.

Medicine & Science in Sports & Exercise, 2011
Position Stand
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Cold-activated brown adipose tissue in healthy men.

New England Journal of Medicine, 2009
W. D. van Marken Lichtenbelt, Joost W. Vanhommerig, N. M. Smulders, Jamie Drossaerts, Gerrit J. Kemerink, N. D. Bouvy, Patrick Schrauwen, G. J. J. Teule   +7 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The World report on ageing and health: a policy framework for healthy ageing.

The Lancet, 2016
J. Beard, A. Officer, I. A. D. Carvalho, R. Sadana, A. Pot, J. Michel, P. Lloyd-Sherlock, J. Epping-jordan, Geeske Peeters, Wahyu Retno Mahanani, J. Thiyagarajan, S. Chatterji   +11 more
semanticscholar   +1 more source

Healthy Mothers. Healthy Babies. Healthy Children [PDF]

American Journal of Public Health, 1924
openaire   +1 more source