Results 221 to 230 of about 338,464 (302)

Working memory filtering at encoding and maintenance in healthy ageing, Alzheimer's and Parkinson's disease. [PDF]

Sci Rep
Toniolo S, Udale R, Klar VS, Maio MR, Attaallah B, Tofaris GK, Hu MT, Manohar SG, Husain M.   +8 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Preparation for healthy ageing: An integrated educational intervention for enhancing knowledge and self-efficacy in intrinsic capacity preservation, midlife condition management, and caregiving in midlife women. [PDF]

J Frailty Aging
Yu R, Yu M, Tong C, Ho F, Hui A, Lui E, Woo J.   +6 more
europepmc   +1 more source

HEALTHY AGING

, 2013
openaire   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Life course socio-economic position and healthy ageing: A systematic review of longitudinal studies

Ye Y, Long C, Chua K, Moreno-Agostino D, Prina M.   +4 more
europepmc   +1 more source

Policies for healthy ageing in response to climate change: Protocol of a systematic review. [PDF]

PLoS One
Asiamah N, Ofosu BO, Effah-Baafi YJ, Awuviry-Newton K, Nkansah J, Saunders B.   +5 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Connections for Ageing Well: A community healthy ageing program to promote social connection. [PDF]

Australas J Ageing
Rae C, Byles J, Denholm S, Holford J, Chojenta C.   +4 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source