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Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source
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Healthy mental ageing

British Menopause Society Journal, 2006
Healthy mental ageing may be defined as the absence of the common disabling mental health problems of older people, especially cognitive decline and depression, accompanied by the perception of a positive quality of life. Older people are particularly prone to negative effects on mental health due to poor physical health.
Leon, Flicker   +2 more
openaire   +2 more sources

Promoting healthy ageing: Development of the Healthy Ageing Quiz

Australasian Journal on Ageing, 2012
Aim:  The aim of this study was to develop the evidence‐based Healthy Ageing Quiz (HAQ).Methods:  Phase 1 activities (focus groups with 33 older adults, literature review and discussion with an advisory panel) informed the development of a draft HAQ.
Elizabeth V, Cyarto   +3 more
openaire   +2 more sources

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