Task-induced brain deactivation reflects the altered default model network in normal and abnormal aging [PDF]
, 2010 The 5th International Symposium on Healthy Aging, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong, 6–7 March ...
Chu, LW +4 more
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BMC Public Health, 2019 Background Urinary incontinence (UI) is known to be more prevalent among women and is associated with decline in quality of life. The aim of our study was to investigate the prevalence, risk factors of urinary incontinence and its impact on quality of ...
Resshaya R. Murukesu +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
DHA supplementation alone or in combination with other nutrients does not modulate cerebral hemodynamics or cognitive function in healthy older adults [PDF]
, 2016 A number of recent trials have demonstrated positive effects of dietary supplementation with the omega-3 polyunsaturated fatty acids (n-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on measures of cognitive function in healthy ...
Kennedy, David O +16 more
core +1 more source
FoodsIn this study, the effects of enzymolysis on physicochemical properties, digestive characteristics, and flora regulation of the meal replacement powder (MRP) were investigated on the basis of the previously obtained compound MRP.
Yongxing Li +8 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Factors affecting healthy aging and its interconnected pathways [PDF]
The process of aging is influenced by factors across different aspects of life including biology, lifestyle, and the surrounding environment. As the global population continues to age it is crucial to understand the complexities involved in maintaining ...
Addo, Kwaku Mari, Khan, Hafiz
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Calorie restriction mimetics from functional foods: impact on promoting a healthy life span [PDF]
, 2017 Aging is a complex process of functional decline at the molecular, cellular, and organ system levels. Even as human life expectancy is being prolonged, age-related diseases continue to be major obstacles for healthy aging and longevity.
Wang, Y, Sun, WY
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structural Basis of Cognitive Compensation in Healthy Brain Aging: Frontal and Occipital Gray Matter Correlates of Cognitive Functioning [PDF]
reservedUnderstanding healthy aging is becoming increasingly important as a larger number of us live longer. Aging involves structural and functional changes in the brain, with the frontal lobe among the first regions to deteriorate, and the occipital ...
ROUNAMA, KIMIA
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