Results 121 to 130 of about 1,887,079 (308)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Monitoring of child-specific activities in ambulatory children with and without developmental disabilities

BMC Pediatrics
Background Pediatric healthcare professionals facilitate children to enhance and maintain a physically active lifestyle. Activity monitors (AM) can help pediatric healthcare professionals assess physical activity in everyday life.
Barbara Engels, Manon A. T. Bloemen, Richard Felius, Karlijn Damen, Eline A. M. Bolster, Harriët Wittink, Raoul H. H. Engelbert, Jan Willem Gorter   +7 more
doaj   +1 more source

Constructions of health, weight and bodily appearance among Indo-Fijian women across three generations : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

, 2014
Discursive constructions of a 'thin ideal' body shape today have often associated the slender body to the idea of a 'healthy weight' and physical beauty.
Nath, Namrata
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Healthy workplaces for a healthy living

The Lancet Public Health, 2022
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A survey of nutritional education within the Holiday Activities and Food programme across England

Frontiers in Public Health
BackgroundNutritional education is a mandatory component of the Holiday Activities and Food (HAF) programme in England, yet there is a paucity of literature exploring how this component is delivered.
Emily K. Round, Paul B. Stretesky, Margaret Anne Defeyter   +2 more
doaj   +1 more source

Living with the Sea: Local Efforts Buffer Effects of Global Change [PDF]

, 2010
Living with the Sea examines the role of MMAs (Marine Managed Areas) in restoring and sustaining healthy oceans, particularly the importance of local management efforts.
John Tschirky, Les Kaufman
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

How to set up and manage a good compost [PDF]

, 2002
This teaching document explains how good compost is made. Compost is the solid, crumble, brownish to dark brown product of an aerobic degradation of biogenic waste or organic material.
Fuchs, Jacques
core