Results 111 to 120 of about 609,352 (314)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Identifying patient subgroups in MASLD and MASH-associated fibrosis: molecular profiles and implications for drug development

Scientific Reports
The incidence of MASLD and MASH-associated fibrosis is rapidly increasing worldwide. Drug therapy is hampered by large patient variability and partial representation of human MASH fibrosis in preclinical models.
Manuel A. González Hernández, Lars Verschuren, Martien P.M. Caspers, Martine C. Morrison, Jennifer Venhorst, Jelle T. van den Berg, Beatrice Coornaert, Roeland Hanemaaijer, Gerard J. P. van Westen   +8 more
doaj   +1 more source

The effect of culinary interventions (cooking classes) on dietary intake and behavioral change: a systematic review and evidence map

BMC Nutrition, 2019
Background Culinary interventions (cooking classes) have been used to improve the quality of dietary intake and change behavior. The aim of this systematic review is to investigate the effects of culinary interventions on dietary intake and behavioral ...
Bashar Hasan, Warren G. Thompson, Jehad Almasri, Zhen Wang, Sumaya Lakis, Larry J. Prokop, Donald D. Hensrud, Kristen S. Frie, Mary J. Wirtz, Angela L. Murad, Jason S. Ewoldt, M. Hassan Murad   +11 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Building a Transition Community

, 2013
Footprints is developing a Transition Community Initiative which will be another distinct area of work within the Healthy Living Project, as part of the group\u27s ongoing endeavours to influence change within the Colin community, tackling health ...
Healthy Food For All
core   +1 more source

Healthy workplaces for a healthy living

The Lancet Public Health, 2022
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The relationship between healthy lifestyle behaviours and outcomes for people living with and beyond cancer: an overview of Systematic Reviews [PDF]

, 2016
There are an extensive number of published evidence reviews examining the influence of lifestyle behaviours on cancer outcomes. Healthy lifestyles are a significant topic of debate in oncology and in policy and practice organisations that support people ...
Grigsby-Duffy, L, Mansfield, L, Kay, T, Kanya, L, O’Connell, N, Meads, C   +5 more
core  

Sugar-sweetened beverages: consumption, purchasing behaviour, and opinions about policy measures in a nationally representative panel of Dutch secondary school adolescents

BMC Public Health
Despite substantial public health efforts, reducing adolescents’ sugar-sweetened beverage (SSB) consumption remains challenging. While much is known about determinants, the underlying motivations for sustained popularity remain unclear.
Rian Pepping, Wilma Waterlander, Barbara Groot-Sluijsmans, Claudia Verhagen, Arnoud P. Verhoeff, Jacob C. Seidell, Vincent Busch   +6 more
doaj   +1 more source