Results 91 to 100 of about 609,352 (314)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Pregnancy, Periods, and “The Pill”: Exploring the Reproductive Experiences of Women with Inflammatory Arthritis

open access: yesACR Open Rheumatology, 2019
Objective Women with inflammatory arthritis appear to have fewer children as compared with healthy women, but few studies have assessed how patients' attitudes and decision making influence their family sizes.
Mehret Birru Talabi   +9 more
doaj   +1 more source

Systematic review of the relationships between sleep duration and health indicators in the early years (0–4 years)

open access: yesBMC Public Health, 2017
Background The objective of this systematic review was to examine for the first time the associations between sleep duration and a broad range of health indicators in children aged 0 to 4 years.
Jean-Philippe Chaput   +9 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Investigation of healthy living strategies in elderly who achieved to live long and healthy.

open access: yesPakistan journal of medical sciences, 2020
PubMed ...
Sahinoz, Turgut, Sahinoz, Saime
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Healthy Valleys : reversing decline in eight rural communities

open access: yes, 2007
Healthy Valleys is a community focused health improvement initiative and our operating principles are our strength – we adopt a community development approach, we are flexible, responsive to communities, effective and innovative.
Coburn, Annette, Wallace, David
core  

Unhealthy Weight Control Practices: Culprits and Clinical Recommendations

open access: yesClinical Medicine Insights: Endocrinology and Diabetes, 2015
Preoccupation with weight status and a desire to lose weight appears common. Many individuals seek “magic bullet” approaches to weight loss and waive the risks of using these products.
Zachary Michael Ferraro   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Capturing occupational risk of airborne disease: An international job-exposure matrix based on five exposure factors

open access: yesScandinavian Journal of Work, Environment & Health
OBJECTIVE: This study aimed to construct a job-exposure matrix (JEM) for the risk of being infected by infectious agents through airborne or droplet transmission in an occupational setting, which might lead to a respiratory disease.
Karen M Oude Hengel   +8 more
doaj   +1 more source

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