Results 61 to 70 of about 609,352 (314)

Development and validation of MyCommunication-Youth: A self-report measure for communicative participation in children, adolescents and young adults

open access: yesJournal of Patient-Reported Outcomes
Background Communicative participation is the most important outcome of speech and language therapy, but there are no measurement instruments for children, adolescents, and young adults.
Eline Alons   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

From Healthy Hearing to Healthy Living: A Holistic Approach

open access: yesEar & Hearing, 2020
The negative consequences of hearing loss go beyond difficulties with communication, having been identified as a major risk factor for injury and illness, social isolation, depression, overall quality of life, and mortality. Hearing loss affects the individual, their families and social network, the broader healthcare system, and the economy ...
Campos, Jennifer L., Launer, Stefan
openaire   +5 more sources

Revising the motivation and confidence domain of the Canadian assessment of physical literacy

open access: yesBMC Public Health, 2018
Background The Motivation and Confidence domain questionnaire in the Canadian Assessment of Physical Literacy (CAPL) was lengthy (36 single items that aggregate to five subscales), and thus burdensome to both participants and practitioners.
Katie E. Gunnell   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ballybeg Family Growing Project

open access: yes, 2013
Ballybeg Family Growing Project aims to engage families living in the Ballybeg estate to raise their awareness and knowledge of healthy eating by providing a practical skills-based education programme of growing and cooking, taking a developmental ...
Healthy Food For All
core   +1 more source

The Role of Technology in Healthy Living Medicine [PDF]

open access: yesProgress in Cardiovascular Diseases, 2017
Health care consumers are taking control of their health information and desire a greater role in managing their health. Approximately 77% of Americans now own a smartphone and the use of health apps have doubled over the past two years. These effects are particularly notable in patients with chronic disease, now representing half the adult population ...
Milani, Richard V., Franklin, Nina C.
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The irony of a rich country: issues of financial access to and availability of healthy food in the Republic of Ireland

open access: yes, 2006
Objective: To determine the weekly financial cost of a diet as recommended by national policy in two parents with two children, single parents with one child and single old people with low income, and begin to identify, in a rich country context ...
Walsh, O, McCarthy, D, Friel, S
core   +1 more source

A RE-AIM evaluation of Healthy Together: a family-centred program to support children’s healthy weights

open access: yes, 2020
Background: Healthy Together (HT) is family-centered program to support healthy eating and physical activity designed for implementation in community organizations serving families who may be experiencing vulnerabilities (e.g., related to low income ...
Nesmith, Catherine   +3 more
core   +1 more source

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