Results 151 to 160 of about 1,504,481 (331)
Obesogenic Environmental Influences on Young Adults: Evidence From Randomized Dormitory Assignment [PDF]
, 2014 This study utilizes a natural experiment—conditionally random dormitory assignments of first-year US college students—to investigate the influence of obesogenic environmental factors in explaining changes in weight and exercise behavior during the 2009 ...
Eisenberg, Daniel +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The role and significance of roof top gardens towards sustainable urban development in Malaysia [PDF]
, 2014 Rooftop garden is a modification of modern landscape which has the potential to contribute towards sustainable urban development. Many studies have highlighted the role of rooftop garden as a tool to assist urban area to solve environmental issues ...
Hussin, Khadijah +2 more
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
THE HEALTHY CITY: PHYSICAL PLANNING TOWARDS SUSTAINABLE URBAN DEVELOPMENT [PDF]
, 2009 Urbanization in Indonesia has been growing rapidly, and is expected to accelerate in the future. It is envisaged that the urban population of the country will grow from 54.7% in 1995 to about 73% I the year 2020.
Yuliastuty, Nany
core
Active Living: Promoting Physical Activity through Healthy Environments
, 2017 Rapid urbanization poses significant public health challenges. By designing activity-friendly environments, designers and planners canenable people to be physically active in their daily routines and shape fundamental aspects of health and well being.
openaire +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Cohort Profile: Growing Up in Wales: The Environments for Healthy Living study [PDF]
International Journal of Epidemiology, 2015 Morgan, Kelly +4 more
openaire +6 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source