Results 41 to 50 of about 191,553 (318)

Cochlear Gene Therapy for Sensorineural Hearing Loss: Current Status and Major Remaining Hurdles for Translational Success

open access: yesFrontiers in Molecular Neuroscience, 2018
Sensorineural hearing loss (SNHL) affects millions of people. Genetic mutations play a large and direct role in both congenital and late-onset cases of SNHL (e.g., age-dependent hearing loss, ADHL).
Wenjuan Zhang   +6 more
doaj   +1 more source

A CRISPR Way to Restore Hearing [PDF]

open access: yesNew England Journal of Medicine, 2018
Preserving Beethoven’s Hearing Researchers have employed a precise means of genetic editing, called CRISPR-Cas9, to “erase” a pathogenic variant that causes hearing loss in a mouse model termed “Beethoven.”
openaire   +2 more sources

A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice

open access: yesEMBO Molecular Medicine, 2018
Normal hearing and synaptic transmission at afferent auditory inner hair cell (IHC) synapses require otoferlin. Deafness DFNB9, caused by mutations in the OTOF gene encoding otoferlin, might be treated by transferring wild‐type otoferlin cDNA into IHCs ...
Hanan Al‐Moyed   +5 more
doaj   +1 more source

Dental amalgam fillings: An under-investigated source of mercury exposure [PDF]

open access: yes, 2019
Dental amalgam fillings, which contain about 50% mercury, have been used since the early 19th century. However, their use has been controversial, particularly because they continually release small amounts of mercury.
Ahlqwist   +55 more
core   +1 more source

Lichen planus of the external auditory canal: Treatment options and review of literature

open access: yesClinical Case Reports, 2020
Medical topic therapies can relieve symptoms associated with lichen planus of external auditory canal. Further, bone‐anchored hearing devices represent an optimal solution for hearing restoration in otic lichen planus.
Francesco Lazzerini   +4 more
doaj   +1 more source

Sensorineural hearing loss after bacterial meningitis in children [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy, 2017
Sensorineural hearing loss – form of hearing loss up to its total lossat which any of the sites of the sound-receiving part can be damaged. The most important problem of patients with sensorineural hearing loss is lack of effective treatment and ...
Aliya Seidullayeva   +5 more
doaj   +1 more source

A Study of Different Otologic Prognostic Factors Determining the Hearing Outcome in Surgical Management of Chronic Otitis Media Squamous Disease

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2022
Introduction The diagnosis of chronic otitis media (COM) implies a permanent abnormality of the pars tensa or flaccida. The definitive treatment of it is surgery. Restoration of hearing is by necessity a secondary consideration.
Amritendu Kamal Maity   +2 more
doaj   +1 more source

Research Of Sensomotor Reaction, Memory And Attention Indicies Under Sensory Deprivation [PDF]

open access: yes, 2019
The article considers the influence of sensory (visual and auditory) deprivation on a sensorimotor response, memory, and attention among 8-11 years old children.
Spryn, O. (Oleksandr)   +2 more
core   +3 more sources

Persistent Stapedial Artery, Oval Window Atresia and Congenital Stapes Agenesis—Case Report

open access: yesMedicina, 2023
Background: The persistent stapedial artery (PSA) is a rare congenital vascular malformation involving the middle ear. It is usually associated with pulsatile tinnitus and/or conductive hearing loss and can account for multiple risks during middle ear ...
Dan Cristian Gheorghe   +3 more
doaj   +1 more source

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