Results 51 to 60 of about 952,675 (273)
Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system
bioRxiv, 2020 Objective. In case of deafness, electrical cochlear implants (eCIs) bypass dysfunctional or lost hair cells by direct stimulation of the auditory nerve.
Lukasz Jablonski +10 more
semanticscholar +1 more source
EMBO Molecular Medicine, 2018 Normal hearing and synaptic transmission at afferent auditory inner hair cell (IHC) synapses require otoferlin. Deafness DFNB9, caused by mutations in the OTOF gene encoding otoferlin, might be treated by transferring wild‐type otoferlin cDNA into IHCs ...
Hanan Al‐Moyed +5 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2018 Sensorineural hearing loss (SNHL) affects millions of people. Genetic mutations play a large and direct role in both congenital and late-onset cases of SNHL (e.g., age-dependent hearing loss, ADHL).
Wenjuan Zhang +6 more
doaj +1 more source
Sensorineural hearing loss after bacterial meningitis in children [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2017 Sensorineural hearing loss – form of hearing loss up to its total lossat which any of the sites of the sound-receiving part can be damaged. The most important problem of patients with sensorineural hearing loss is lack of effective treatment and ...
Aliya Seidullayeva +5 more
doaj +1 more source
Bengal Journal of Otolaryngology and Head Neck Surgery, 2022 Introduction The diagnosis of chronic otitis media (COM) implies a permanent abnormality of the pars tensa or flaccida. The definitive treatment of it is surgery. Restoration of hearing is by necessity a secondary consideration.
Amritendu Kamal Maity +2 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Emerging approaches for restoration of hearing and vision
Physiological Reviews, 2020 Impairments of vision and hearing are highly prevalent conditions limiting the quality of life and presenting a major socioeconomic burden. For long, retinal and cochlear disorders have remained intractable for causal therapies, with sensory rehabilitation limited to glasses, hearing aids, and electrical cochlear or retinal implants.
Kleinlogel, Sonja +4 more
openaire +4 more sources
Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications
Advanced Materials, EarlyView.Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib +10 more
wiley +1 more source
Autosomal Recessive Non-Syndromic Deafness: Is AAV Gene Therapy a Real Chance?
Audiology ResearchThe etiology of sensorineural hearing loss is heavily influenced by genetic mutations, with approximately 80% of cases attributed to genetic causes and only 20% to environmental factors.
Davide Brotto +3 more
doaj +1 more source