Results 21 to 30 of about 952,675 (273)

Toward Optogenetic Hearing Restoration

open access: yesAnnual Review of Neuroscience
The cochlear implant (CI) is considered the most successful neuroprosthesis as it enables speech comprehension in the majority of the million otherwise deaf patients. In hearing by electrical stimulation of the auditory nerve, the broad spread of current from each electrode acts as a bottleneck that limits the transfer of sound frequency information ...
Huet, Antoine   +3 more
openaire   +5 more sources

Hearing Restoration with Cochlear Implantation in Patients Deafened after Blunt Head Trauma. [PDF]

open access: yesJ Int Adv Otol, 2018
OBJECTIVES The objective of the study was to assess the outcomes of cochlear implantation in patients deafened following blunt head trauma. MATERIAL AND METHODS Retrospective case series review of seven patients post-lingually deafened following blunt ...
Lachowska M   +5 more
europepmc   +2 more sources

Classification of facial nerve aberration in congenital malformation of middle ear: Implications for surgery of hearing restoration. [PDF]

open access: yesJ Otol, 2018
Objectives Facial nerve aberration is the most troublesome situation in congenital malformations of middle ear. The aim of our study is to investigate its imaging and clinical features as well as relevant choice of surgical techniques for hearing ...
Hao J, Xu L, Li S, Fu X, Zhao S.
europepmc   +2 more sources

Understanding Molecular Evolution and Development of the Organ of Corti Can Provide Clues for Hearing Restoration. [PDF]

open access: yesIntegr Comp Biol, 2018
The mammalian hearing organ is a stereotyped cellular assembly with orderly innervation: two types of spiral ganglion neurons (SGNs) innervate two types of differentially distributed hair cells (HCs).
Jahan I, Elliott KL, Fritzsch B.
europepmc   +2 more sources

Hearing Restoration in Neurofibromatosis Type II Patients. [PDF]

open access: yesYonsei Med J, 2016
Patients with neurofibromatosis type II will eventually succumb to bilateral deafness. For patients with hearing loss, modern medical science technology can provide efficient hearing restoration through a number of various methods.
Lee JM   +4 more
europepmc   +2 more sources

Towards optogenetic approaches for hearing restoration

open access: yesBiochemical and Biophysical Research Communications, 2020
Hearing impairment (HI) is the most frequent sensory deficit in humans. As yet there is no causal therapy for sensorineural HI - the most common form - that results from cochlear dysfunction. Hearing aids and electrical cochlear implants (eCIs) remain the key options for hearing rehabilitation. The eCI, used by more than 0.7 Mio people with profound HI
Moser, Tobias, Dieter, Alexander
openaire   +4 more sources

Neurofibromatosis 2: hearing restoration options. [PDF]

open access: yesBraz J Otorhinolaryngol, 2012
Neurofibromatosis 2 (NF2) is an autosomal dominant disease in which hearing loss is predominant. Auditory restoration is possible using cochlear implants (CI) or auditory brainstem implant (ABI).To assess the auditory results of CI and ABI in NF2 patients and review the literature.Four NF2 patients were prospectively evaluated.
Monteiro TA   +5 more
europepmc   +3 more sources

A physiological and behavioral system for hearing restoration with cochlear implants.

open access: yesJ Neurophysiol, 2016
Cochlear implants are neuroprosthetic devices that provide hearing to deaf patients, although outcomes are highly variable even with prolonged training and use.
King J   +4 more
europepmc   +2 more sources

Hair cell regeneration, reinnervation, and restoration of hearing thresholds in the avian hearing organ

open access: yesCell Reports
Summary: Hearing starts, at the cellular level, with mechanoelectrical transduction by sensory hair cells. Sound information is then transmitted via afferent synaptic connections with auditory neurons.
Mitsuo P. Sato   +2 more
doaj   +2 more sources

Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model

open access: yesFrontiers in Molecular Neuroscience, 2021
Clinical management of auditory synaptopathies like other genetic hearing disorders is currently limited to the use of hearing aids or cochlear implants.
David Oestreicher   +12 more
doaj   +1 more source

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